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2024

394. Yan Li, Wuzhe Fan, Xiang Gu, Shaopeng Liu, Tingting He, Shuangquan Gou, Weilin Meng, Meng Li, Xihong Liu, Yu Ren, Chao Qi*, Kaiyong Cai*. Biodegradable ferric phosphate nanocarriers with tumor-specific activation and glutathione depletion for tumor self-enhanced ferroptosis and chemotherapy. Adv Funct Mater 2024, 2313540.

393. Weilin Meng, Ze Lin, Xuan Cheng, Shuangqian Gou, Rong Wang, Pengzhen Bu, Yan Li, Bobin Mi*, Yongsheng Yu*, Qian Feng*, Kaiyong Cai*. Thiourea-cation chelation based hydrogel and its application as antibacterial dressing for the repair of diabetic wound. Adv Funct Mater 2024, 2314202.

392. Yanqiu Wang, Lu Tan, Wanqian Zhang, Yi Yang, Changqing Li, Hongli Li, Kaiyong Cai, Yan Hu, Zhong Luo*, Minghan Liu*. Injectable Dynamic Hydrogel with Responsive Mechanical Reinforcing Ability Reverses Intervertebral Disc Degeneration by Suppressing Ferroptosis and Restoring Matrix Homeostasis. Adv Funct Mater 2024, 2310416.

391. Kangkang Zha†, Wenqian Zhang†, Weixian Hu†, Meijun Tan†, Shengming Zhang, Yongsheng Yu, Shuangquan Gou, Pengzhen Bu, Bikun Zhou, Yanan Zou, Yuan Xiong, Bobin Mi*, Guohui Liu*, Qian Feng*, Kaiyong Cai*. Three-step regenerative strategy: multifunctional bilayer hydrogel for combined photothermal/photodynamic therapy to promote drug-resistant bacteria-infected wound healing. Adv Funct Mater 2024,34, 2308145.

390. Meng Li, Jing Wu*, Wenbo Geng, Pengfei Gao, Yulu Yang, Xuan Li, Kun Xu, Qiang Liao, Kaiyong Cai*. Interaction pathways of implant metal localized corrosion and macrophage inflammatory reactions. Bioactive Materials 2024, 31, 355-367.

389. Yuehui Wang, Sigal Rencus-Lazar, Haoran Zhou, Yuanyuan Yin*, Xuemei Jiang, Kaiyong Cai, Ehud Gazit*, Wei Ji*. Bioinspired Amino Acid Based Materials in Bionanotechnology: From Minimalistic Building Blocks and Assembly Mechanism to Applications. ACS Nano 2024, 18(2), 1257-1288.

388. Lingli Ma, Ya Ma, Qiang Gao, Shengsheng Liu, Zhenhua Zhu, Xiaoxiao Shi, Fangyin Dai*, Rui L. Reis, Subhas C. Kundu, Kaiyong Cai*, Bo Xiao*. Mulberry Leaf Lipid Nanoparticles: A Naturally Targeted CRISPR/Cas9 Oral Delivery Platform for Alleviation of Colon Disease. Small 2024, 2307247.

387. Genhua Liu, Ruichen Ma, Peng Liu*, Kui Wang*, Kaiyong Cai*. An injectable nanocomposite hydrogel prevents postoperative tumor recurrence and wound infection via synergistic photothermal-chemo-therapy. Journal of Colloid and Interface Science 2024, 655, 809–821.

386. Jingpi Gao, Yangyang Yan, Shegan Gao∗, Heying Li, Xiantao Lin, Ji Cheng, Yan Hu, Kaiyong Cai*, Xiaozhi Zhang*, Jinghua Li*. Heterogeneous Cu2O-SnO2 doped polydopamine fenton-like nanoenzymes for synergetic photothermal-chemodynamic antibacterial application. Acta Biomaterialia 2024, 173, 420–431.

385. Xiaodong Chen, Shuohan He, Yilong Dong, Maohua Chen, Zengzilu Xia*, Kaiyong Cai*, Yan Hu*. Cobalt-doped layered hydroxide coating on titanium implants promotes vascularization and osteogenesis for accelerated fracture healing. Materials Today Bio 2024, 24, 100912.

384. Shaopeng Liu, Dan Peng, Shuohan He, Xuan Li, Yi Wu, Xin Liu, Yang Zhang, Peng Liu*, Kaiyong Cai*. Ternary low-temperature phototherapy nano-system for the treatment of diabetic wounds. J Mater Chem B 2024, 12, 264-274.

383. Yingying Tan, Yao Ding, Shaopeng Liu, Peng Liu*, Kaiyong Cai*. Titanium-based substrate modified with nanoenzyme for accelerating the repair of bone defect. Colloids and Surfaces B: Biointerfaces 2024, 234, 113737.

2023

382. Ke Zhang, Chao Qi*, Kaiyong Cai*. Manganese-based tumor immunotherapy. Adv Mater 2023, 35, 2205409.

381. Shuangquan Gou, Gangyang Wang, Yanan Zou, Wenbo Geng, Tingting He, Zizhen Qin, Lingbin Che*, Qian Feng*, Kaiyong Cai*. Non-pore Dependent and MMP-9 Responsive Gelatin/Silk Fibroin Composite Microparticles as Universal Delivery Platform for Inhalation Treatment of Lung Cancer. Adv Mater 2023,35, 2303718

380. Shuai Wang, Jixi Huang, Hanyin Zhu, Jing Zhu, Zhenqiang Wang, Yuxin Xing, Xiyue Xie, Kaiyong Cai, Jixi Zhang*. Nanomodulators Capable of Timely Scavenging ROS for Inflammation and Prognosis Control Following Photothermal Tumor Therapy. Adv Funct Mater 2023, 33, 2213151.

379. Dan Li, Danyang Wang, Yulu Yang, Pengfei Gao, Wuzhe Fan, Xianhui Zhang, Yu Tang, Weihu Yang*, Kaiyong Cai*. Caffeic Acid-Deferoxamine Self-Polymerization Coating on Ti Implant Promotes Osteointegration by Synergetic Regulation of Multi-Pathways in ONFH Mechanism. Adv Funct Mater 2023, 33, 2212016.

378. Zhang Yuan*, Jianshuang Wu, Yao Xiao, Huan Yang, Siyu Meng, Liangliang Dai*, Peng Li*, Kaiyong Cai*. A photo-therapeutic nanocomposite with bio-responsive oxygen self-supplying combats biofilm infections and inflammation from drug-resistant bacteria. Adv Funct Mater 2023, 33, 2302908.

377. Shuangquan Gou, Weilin Meng, Adriana C. Panayi, Rong Wang, Rui Zhang, Pengfei Gao, Tingting He, Wenbo Geng, Shi Hu, Yongsheng Yu*, Qian Feng*, Kaiyong Cai*. Bioresponsive self-reinforcing sericin/silk fibroin hydrogel for relieving the immune-related adverse events in tumor immunotherapy. Adv Funct Mater 2023, 33, 2213867.

376. Lu Tan, Menghuan Li, Hang Chen, Yuchen Zhang, Yuan Liu, Maohua Chen, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Dynamic hydrogel with environment-adaptive autonomous wound-compressing ability enables rapid hemostasis and inflammation amelioration for hemorrhagic wound healing. Nano Today 2023,52,101962.

375. Beining Yang, Fanze Meng, Jihao Zhang, Kerun Chen, Siyu Meng, Kaiyong Cai, Yanli Zhao , Liangliang Dai. Engineered drug delivery nanosystems for tumor microenvironment normalization therapy. Nano Today 2023, 19, 101766.

374. Ke Li†, Kun Xu†, Shaopeng Liu, Ye He*, Meijun Tan, Yulan Mao, Yulu Yang, Jing Wu, Qian Feng, Zhong Luo, Kaiyong Cai*. All-in-one Engineering Multifunctional Nanoplatforms for Sensitizing Tumor Low-Temperature Photothermal Therapy in vivo. ACS Nano 2023, 17, 20218-20236.

373. Xu Zhang, Zhang Yuan*, Jianshuang Wu, Ye He, Guifang Lu, Dan Zhang, Yan Zhao, Rongqian Wu, Yi Lv, Kaiyong Cai*, Shuixiang He*. An Orally-Administered Nanotherapeutics with Carbon Monoxide Supplying for Inflammatory Bowel Disease Therapy by Scavenging Oxidative Stress and Restoring Gut Immune Homeostasis. ACS Nano 2023, 17(21), 21116-21133.

372. Xuan Li, Xinxin Luo, Ye He, Kun Xu, Yao Ding, Pengfei Gao, Bailong Tao, Meng Li, Meijun Tan, Shaopeng Liu, Peng Liu*, Kaiyong Cai*. Micro-nano Titanium Accelerates Mesenchymal Stem Cells Aging through The Activation of Senescence-associated Secretory Phenotype. ACS Nano 2023, 17(22), 22885-22900.

371. Tingting He, Lu Wang, Shuangquan Gou, Lu Lu, Genhua Liu, Kui Wang, Yulu Yang, Qiaojian Duan, Wenbo Geng, Peng Zhao*, Zhong Luo*, Kaiyong Cai*. Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium Bifidum to Boost Chemo-immunotherapy. ACS Nano 2023, 17, 9953-9971.

370. Maohua Chen, Menghuan Li, Xijiao Ren, Fei Zhou, Yanan Li, Lu Tan, Zhong Luo*, Kaiyong Cai*, Yan Hu*. DNAzyme Nanoconstruct-Integrated Autonomously-Adaptive Coatings Enhance Titanium-Implant Osteointegration by Cooperative Angiogenesis and Vessel Remodeling. ACS Nano 2023, 17, 15942-15961.

369. Kangkang Zha, Yuan Xiong, Wenqian Zhang, Meijun Tan, Weixian Hu, Ze Lin, Peng Cheng, Li Lu, Kaiyong Cai, Bobin Mi*, Qian Feng*, Yanli Zhao*, Guohui Liu*. Waste to Wealth: Near-Infrared/pH Dual-Responsive Copper-Humic Acid Hydrogel Films for Bacteria-Infected Cutaneous Wound Healing. ACS Nano 2023, 17, 17199-17216.

368. Fei Zhou, Menghuan Li, Maohua Chen, Maowen Chen, Xiaodong Chen, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Redox Homeostasis Strategy for Inflammatory Macrophage Reprogramming in Rheumatoid Arthritis Based on Ceriaoxide Nanozyme-complexed Biopolymeric Micelles. ACS Nano 2023, 17, 4358-4372.

367. Yuxin Xing, Lin Li, Yuhua Chen, Lu Wang, Shuqi Tang, Xiyue Xie, Shuai Wang, Jixi Huang, Kaiyong Cai*, and Jixi Zhang*. Flower-like Nanozyme with Highly Porous Carbon Matrix Induces Robust Oxidative Storm against Drug-Resistant Cancer. ACS Nano 2023, 17, 6731−6744.

366. Ke Li, Kun Xu, Ye He, Yulu Yang, Meijun Tan, Yulan Mao, Yanan Zou, Qian Feng, Zhong Luo, Kaiyong Cai*. Oxygen Self-Generating Nanoreactor Mediated Ferroptosis Activation and Immunotherapy in Triple-Negative Breast Cancer. ACS Nano 2023, 17, 5, 4667-4687.

365. Pengfei Gao, Yangpeng Zuo, Yulu Yang, Jinxiu Yu, Wuzhe Fan, Ruqing Bai*, Weihu Yang *, Kaiyong Cai*. PB@EGCG-Sr nanocoating design on titanium surface: to achieve short-term rapid osseointegration and on-demand photothermal long-term osteogenesis. Chem Eng J 2023, 474,145608.

364. Yan Huang, Maowen Chen, Yiding Shen, Xinkun Shen*, Menghuan Li, Yanan Li, Yuan Liu, Kaiyong Cai, Zhong Luo*, Yan Hu*. Bone-targeting cell membrane-engineered CaCO3-based nanoparticles restore local bone homeostasis for microenvironment-responsive osteoporosis treatment. Chem Eng J 2023, 470, 144145.

363. Yuehui Wang#, Shuaijie Liu#, Lingling Li, Hui Li, Yuanyuan Yin, Sigal Rencus-Lazar, Sarah Guerin, Damien Thompson, Rusen Yang, Kaiyong Cai*, Ehud Gazit*, Wei Ji*. Manipulating the Piezoelectric Response of Amino Acid-Based Assemblies by Supramolecular Engineering. J Am Chem Soc 2023, 145, 15331-15342.

362. Rong Huang, Chun-Hua Huang*, Jing Chen, Zhu-Ying Yan, Miao Tang, Jie Shao, Kaiyong Cai, Ben-Zhan Zhu*. Unprecedented enantio-selective live-cell mitochondrial DNA super-resolution imaging and photo-sensitizing by the chiral ruthenium polypyridyl DNA “light-switch”. NUCLEIC ACIDS RESEARCH 2023, 51, 11981–11998.

361. Meng Li, Jing Wu*, Wenbo Geng, Yulu Yang, Xuan Li, Kun Xu, Ke Li, Yan Li, Qiaojian Duan, Pengfei Gao, Kaiyong Cai*. Regulation of localized corrosion of 316L stainless steel on osteogenic differentiation of bone morrow derived mesenchymal stem cells. Biomaterials 2023,301,122262.

360. Xinyue Ge†, Hong Wen†, Liqi Li*, Yang Fei, Rui Xue, Zhuo Cheng, Yanan Li, Kaiyong Cai, Menghuan Li*, Zhong Luo*. Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment. Biomaterials 2023, 299,122184.

359. Shi Mo, Kaiwei Tang, Qing Liao, Lingxia Xie, Yuzheng Wu, Guomin Wang, Qingdong Ruan, Ang Gao, Yuanliang Lv, Kaiyong Cai, Liping Tong, Zhengwei Wu, Paul K. Chu, Huaiyu Wang*. Tuning the arrangement of lamellar nanostructures: achieving the dual function of physically killing bacteria and promoting osteogenesis. Materials Horizons 2023, 10, 881-888.

358. Yuhua Chen, Yuxin Xing, Zhenqiang Wang, Lin Li, Hailing Wang, Shuqi Tang, Kaiyong Cai, Jixi Zhang*. Dual factor coactivatable fluorescent nanosensor with boosted cytoplasmic biomarker accessibility toward selective tumor imaging. Biosensors and Bioelectronics 2023, 223, 115026.

357. Xiyue Xie, Kaifei Jin, Zhenqiang Wang, Shuai Wang, Jing Zhu, Jixi Huang, Shuqi Tang, Kaiyong Cai, Jixi Zhang*. Constraint Coupling of Redox Cascade and Electron Transfer Synchronization on Electrode-Nanosensor Interface for Repeatable Detection of Tumor Biomarkers. Small Methods 2023, 2301330.

356. Kai Lin, Ao Xia, Yun Huang, Xianqing Zhu, Xun Zhu, Kaiyong Cai, Zidong Wei, Qiang Liao*. How can vanillin improve the performance of lignocellulosic biomass conversion in an immobilized laccase microreactor system? Bioresource Technology 2023, 374, 128775.

355. Jinxiu Yu#, Pengfei Gao#, Yulu Yang, Dan Peng, Xianhui Zhang, Danyang Wang, Weihu Yang*, Yu Tang*, Kaiyong Cai*. Promoting osseointegration of titanium by pH-responsive releasing of H2S and optimizing polarization time for macrophages. Composites Part B 2023, 253, 110554.

354. Yao Ding, Bailong Tao, Ruichen Ma, Xin Zhao, Peng Liu*, Kaiyong Cai*. Surface modification of titanium implant for repairing/improving microenvironment of bone injury and promoting osseointegration. Journal of Materials Science & Technology 2023, 143, 1-11.

353. Dan Li, Danyang Wang, Ye He, Bailong Tao, Xiaoxia Liu, Yulu Yang, Lu Tan, Yuchen Zhang, Jingwei Hu, Weihu Yang*, Yu Tang*, Kaiyong Cai*. A HAase/NIR responsive surface on titanium implants for treating bacterial infection and improving osseointegration. Journal of Materials Science & Technology 2023, 143, 93-106.

352. Wenbo Geng, Xuezhe Liu, Bailong Tao, Ye He, Ke Li, Pengfei Gao, Qian Feng, Peng Zhao*, Zhong Luo, Kaiyong Cai*. Nitric Oxide Scavenging and Hydrogen Sulfide Production Synergistically Treat Rheumatoid Arthritis. Advanced Healthcare Materials. 2023, 12, 2202380.

351. Kun Xu, Ke Li, Ye He, Xuan Li, Chuanchuan Lin, Jing Wu, Shaopeng Liu, Yao Ding, Yulu Yang, Shuangquan Gou, Peng Liu*, Kaiyong Cai*. Functional titanium substrates synergetic photothermal therapy for enhanced antibacterial and osteogenic performance via immunity regulation. Advanced Healthcare Materials 2023, 12, 2300494.

350. Yao Ding, Genhua Liu, Shaopeng Liu, Xuan Li, Kun Xu, Peng Liu*, Kaiyong Cai*. A multi-function hydrogel-coating engineered implant for rescuing biofilm infection and boosting osseointegration by macrophage-related immunomodulation. Advanced Healthcare Materials 2023, 12, 2300722.

349. Yulu Yang, Rui Chen, Ke Li, Pengfei Gao, Yi Gong, Weihu Yang*, Kaiyong Cai*. Design of manganese ion coated Prussian blue nanocarrier for the therapy of refractory diffuse large B-cell lymphoma based on a comprehensive analysis of ferroptosis regulators from clinical cases. Nano Research 2023,16, 5265-5278.

348. Maoyuan Sun#, Yan Li#, Wenli Zhang, Xiang Gu, Rong Wen, Ke Zhang, Jinning Mao, Chengyao Huang, Xiong Zhang, Mao Nie, Zhiwen Zhang, Chao Qi*, Kaiyong Cai*, Guodong Liu*. Allomelanin-based biomimetic nanotherapeutics for orthotopic glioblastoma targeted photothermal immunotherapy. Acta Biomaterialia 2023, 166, 552-566.

347. Jiawu Yu†, Yuchen Zhang†, Liqi Li, Yang Xiang, Xuemei Yao, Youbo Zhao, Kaiyong Cai, Menghuan Li*, Zhongjun Li*, Zhong Luo*. Coordination-Driven FBXW7 DNAzyme-Fe Nanoassembly Enables a Binary Switch of Breast Cancer Cell Cycle Checkpoint Responses for Enhanced Ferroptosis-Radiotherapy. Acta Biomaterialia 2023,169,434-450.

346. Yao Ding, Ruichen Ma, Genhua Liu, Xuan Li, Kun Xu, Peng Liu*, Kaiyong Cai*. Fabrication of a new hyaluronic acid/gelatin nanocomposite hydrogel coating on titanium-based implant for treating biofilm infection and excessive inflammatory response. ACS Applied Materials & Interfaces 2023, 15, 13783−13801.

345. Yingqi Liu, Xuemei Yao, Youbo Zhao, De Fang, Lei Shi, Li Yang, Guanbin Song, Kaiyong Cai, Liqi Li, Qin Deng, Menghuan Li*, Zhong Luo*. Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells. Cell Reports 2023, 42, 113213.

344. Kaifei Jin, Xiyue Xie, Jing Zhu, Zhenqiang Wang, Yuxin Xing, Lu Wang*, Kaiyong Cai, Jixi Zhang*. Highly repeatable detection of miRNAs in complex biological mixtures mediated by magnetically separable spherical nucleic acids and homogeneous signal amplification. Sensors and Actuators: B Chemical 2023,393,134191.

343. Yuan Liu‡, Lu Tan‡, Yan Huang, Maohua Chen, Menghuan Li, Kaiyong Cai*, Zhong Luo* and Yan Hu*. Multifunctional antibiotics-free hydrogel dressings with self-regulated nitric oxide-releasing kinetics for improving open wound healing. J Mater Chem B 2023, 11, 3650-3668.

342. Heying Li#, Shaowen Cheng#, Jingming Zhai, Kun Lei*, Ping Zhou, Kaiyong Cai*, Jinghua Li*. Platinum based theranostics nanoplatforms for antitumor applications. J Mater Chem B. 2023, 11, 8387–8403.

341. Zhuo Cheng, Yan Hu, Yingqi Liu, Xuan Wang, Rui Xue, Kaiyong Cai, Liqi Li*, Menghuan Li*, Zhong Luo*. Engineered In-Situ-Forming Biomimetic Hydrogel with Self-Regulated Immunostimulatory Capacity Promotes Postoperative Tumor Treatment. Fundamental Research 2023, In Press.

340. Jingpi Gao, Qinghao He, Gaofeng Liang*, Lingqing Luo, Xiaoran Liu, Kaiyong Cai*, Jinghua Li*. Heterogeneous alloyed CuSnO-DopaCube mediated photo-Fenton and photothermal synergistic catalysis for dye elimination. Journal of Alloys and Compounds 2023,960, 170737.

339. Jingpi Gao, Ping Yang, Heying Li, Nan Li, Xiaoran Liu*, Kaiyong Cai, Jinghua Li*. Advances in anti-tumor research based on bionic micro-nano technology. J DRUG DELIV SCI TEC 2023, 86, 104674.

338. Yehong Huo, Jian Hu, Yuanyuan Yin, Peng Liu, Kaiyong Cai, Wei Ji*. Self‐assembling peptide‐based functional biomaterials. ChemBioChem 2023,24, e2022005.

337. Lu Wang, Shuqi Tang, Lin Li, Kaifei Jin, Xiyue Xie, Yuhua Chen, Kaiyong Cai*, Jixi Zhang*. Nucleic Acids Enabled-Interfacial Engineering for Biomarker Sensing with Distance Constraint Effects. Adv. Sensor Res. 2023, 2, 2200062.

2022

336. Yuxin Xing, Lu Wang, Liucan Wang, Jixi Huang, Shuai Wang, Xiyue Xie, Jing Zhu, Tao Ding, Kaiyong Cai, Jixi Zhang*. Flower-Like Nanozymes with Large Accessibility of Single Atom Catalysis Sites for ROS Generation Boosted Tumor Therapy. Advanced Functional Materials 2022, 32, 2111171.

335. Zhang Yuan, Jianshuang Wu, Zhenxiang Fu, Siyu Meng, Liangliang Dai*, Kaiyong Cai*. Polydopamine-Mediated Interfacial Functionalization of Implants for Accelerating Infected Bone Repair through Light-Activatable Antibiosis and Carbon Monoxide Gas Regulated Macrophage Polarization. Advanced Functional Materials 2022, 32, 2200374.

334. Zhenqiang Wang, Ruirui Jia, Yuhua Chen, Xiyue Xie, Shuai Wang, Jixi Huang, Meizhen Zhou, Kaiyong Cai*, Jixi Zhang*. Supramolecular semiquinone radicals confined with DNAzymes for dissipative ROS generation and therapy. Nano Today 2022, 43, 101402.

333. Kui Wang, Jie Chen, Lin Lin, Nan Yan, Weihu Yang, Kaiyong Cai, Huayu Tian, Xuesi Chen. Anion receptor-mediated multicomponent synergistic self-assembly of porphyrin for efficient phototherapy to elicit tumor immunotherapy. Nano Today 2022, 46, 101579.

332.Maowen Chen†, Dong Wang†, Menghuan Li, Ye He, Tingting He, Maohua Chen, Yan Hu*, Zhong Luo*, Kaiyong Cai*. Nanocatalytic Biofunctional MOF Coating on Titanium Implants Promotes Osteoporotic Bone Regeneration through Cooperative Pro-osteoblastogenesis MSC Reprogramming. ACS Nano 2022, 16, 15397-15412.

331. Ke Li, Chuanchuan Lin, Menghuan Li, Kun Xu, Ye He, Yulan Mao, Lu Lu, Wenbo Geng, Xuemin Li, Zhong Luo*, Kaiyong Cai*. Multienzyme-like Reactivity Cooperatively Impairs Glutathione Peroxidase 4 and Ferroptosis Suppressor Protein 1 Pathways in Triple-Negative Breast Cancer for Sensitized Ferroptosis Therapy. ACS Nano 2022, 16, 2381−2398.

330. Yanan Li, Menghuan Li, Li Liu, Chencheng Xue, Yang Fei, Xuan Wang, Yuchen Zhang, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Cell-Specific Metabolic Reprogramming of Tumors for Bioactivatable Ferroptosis Therapy. ACS Nano 2022, 16, 3965-3984.

329. Liangliang Dai, Mengjiao Yao, Zhenxiang Fu, Xiang Li, Xinmin Zheng, Siyu Meng, Zhang Yuan, Kaiyong Cai*, Hui Yang*, Yanli Zhao*. Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy. Nature Communications 2022, 13, 2688.

328. Xuan Wang, Yingqi Liu, Chen-Cheng Xue, Yan Hu, Yuanyuan Zhao, Kaiyong Cai, Menghuan Li, Zhong Luo*. A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses. Nature Communications 2022, 13(1) 5685.

327. Maohua Chen, Yuting Sun, Yanhua Hou, Zhong Luo*, Menghuan Li, Yujia Wei, Maowen Chen, Lu Tan, Kaiyong Cai*, Yan Hu*. Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in peri-implant space and bone formation in osteoporosis microenvironment. Bioactive Materials 2022, 18, 51-67.

326. Jingwei Hu, Yao Ding, Bailong Tao, Zhang Yuan, Yulu Yang, Kun Xu, Xuan Li, Peng Liu*, Kaiyong Cai*. Surface modification of titanium substrate via combining photothermal therapy and quorum-sensing-inhibition strategy for improving osseointegration and treating biofilm-associated bacterial infection.Bioactive Materials 2022, 18, 228-241.

325. Wei Ji, Hui Yuan, Bin Xue, Sarah Guerin, Hui Li, Lei Zhang, Yanqing Liu, Linda J. W. Shimon, Mingsu Si, Yi Cao, Wei Wang, Damien Thompson, Kaiyong Cai, Rusen Yang* Ehud Gazit*. Co-Assembly Induced Solid-State Stacking Transformation in Amino Acid-based Crystals with Enhanced Physical Properties. Angewandte Chemie International Edition 2022, 61, e2022012.

324. Yang Xiang, Qian Ran, Chun Wu, Luping Zhou, Weiwei Zhang, Lixin Xiang, Yanni Xiao, Li Chen, Yan Chen, Xuelian Chen, Andres Stucky, Shengwen Calvin Li, Jiang F. Zhong, Zhongjun Li*, Kaiyong Cai*. Single-cell transcriptomics uncovers the impacts of titanium dioxide nanoparticles on human bone marrow stromal cells. Chemical Engineering Journal 2022, 440, 135814.

323. Jingming Zhai, Jingpi Gao, Jianbo Zhang, Dechun Liu, Shegan Gao, Yangyang Yan, Keke Zhang, Kaiyong Cai*, Fabiao Yu, Manping Lin, Jinghua Li*. Concave octahedral PtCu nanoframes mediated synergetic photothermal and chemodynamic tumor therapy. Chemical Engineering Journal 2022, 442,136172.

322. Kai Lin, Ao Xia*, Yun Huang, Xianqing Zhu, Kaiyong Cai, Zidong Wei, Qiang Liao*.  Efficient production of sugar via continuous enzymatic hydrolysis in a microreactor loaded with cellulose. Chemical Engineering Journal 2022,445, 136633.

321. Lu Tan, Yan Hu*, Menghuan Li, Yuchen Zhang, Chencheng Xue, Maohua Chen, Zhong Luo*, Kaiyong Cai*. Remotely-activatable extracellular matrix-mimetic hydrogel promotes physiological bone mineralization for enhanced cranial defect healing. Chemical Engineering Journal 2022,431, 133382.

320. Maowen Chen, Yan Hu*, Yanhua Hou, Menghuan Li, Lu Tan, Maohua Chen, Wenbo Geng, Bailong Tao, Zhong Luo*, Kaiyong Cai*. Magnesium/gallium-layered nanosheets on titanium implants mediate osteogenic differentiation of MSCs and osseointegration under osteoporotic condition. Chemical Engineering Journal 2022,427, 130982.

319. Wei Ji*, Bin Xue, Yuanyuan Yin, Yuehui Wang, Sarah Guerin, Yuanqi Cheng, Linda J. W. Shimon, Yu Chen*, Damien Thompson, Rusen Yang, Yi Cao, Wei Wang, Kaiyong Cai, and Ehud Gazit*. Modulating the Electromechanical Response of Bio-Inspired Amino Acid-Based Architectures through Supramolecular Co-Assembly. Journal of the American Chemical Society 2022, 144, 40, 18375-18386.

318. Xuan Li, Kun Xu, Ye He, Bailong Tao, Ke Li, Chuanchuan Lin, Jingwei Hu, Jing Wu, Yi Wu, Shaopeng Liu, Peng liu*, Huaiyu Wang, Kaiyong Cai*. ROS-responsive hydrogel coating modified titanium promotes vascularization and osteointegration of bone defects by orchestrating immunomodulation. Biomaterials 2022, 287, 121683.

317. Yulu Yang, Rui Chen, Yi Gong*, Weihu Yang*, Ke Li, Wuzhe Fan, Shuangquan Gou, Pengfei Gao, Tingting He, Kaiyong Cai*. Double-drug loading upconversion nanoparticles for monitoring and therapy of a MYC/BCL6-positive double-hit diffuse large B-cell lymphoma. Biomaterials 2022, 287, 121607.

316. Maohua Chen, Menghuan Li, Yujia Wei, Chencheng Xue, Maowen Chen, Yang Fei, Lu Tan, Zhong Luo*, Kaiyong Cai*, Yan Hu*. ROS-activatable biomimetic interface mediates in-situ bioenergetic remodeling of osteogenic cells for osteoporotic bone repair. Biomaterials 2022,291, 121878.

315. Dong Wang, Mao-Wen Chen, Yu-Jia Wei, Wen-Bo Geng, Yan Hu*, Zhong Luo*, Kai-Yong Cai*. Construction of Wogonin Nanoparticle-Containing Strontium-Doped Nanoporous Structure on Titanium Surface to Promote Osteoporosis Fracture Repair. Advanced Healthcare Materials 2022, 11, 1, 2201405.

314. Wenbo Geng, Xuezhe Liu, Bailong Tao, Ye He, Ke Li, Pengfei Gao, Qian Feng, Peng Zhao*, Zhong Luo, Kaiyong Cai*. Nitric Oxide Scavenging and Hydrogen Sulfide Production Synergistically Treat Rheumatoid Arthritis. Advanced Healthcare Materials. 2022, in press.

313. Lu Tan, Menghuan Li, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Black phosphorus biomaterials for photo-controlled bone tissue engineering. Composites Part B: Engineering 2022, 246, 110245.

312. Zhenxiang Fu, Huiping Du, Siyu Meng, Mengjiao Yao, Pan Zhao, Xiang Li, Xinmin Zheng, Zhang Yuan*, Hui Yang, Kaiyong Cai, Liangliang Dai*. Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES. Materials Today Bio 2022, 16, 100449.

311. Xiaoxia Liu, Danyang Wang, Shuai Wang, Wuzhe Fan, Yulu Yang, Pengfei Gao, Maowen Chen, Weihu Yang*, Kaiyong Cai*. Promoting osseointegration by in situ biosynthesis of metal ion-loaded bacterial cellulose coating on titanium surface.  Carbohydrate Polymers 2022, 297, 120022.

310. Jixi Huang, Shuai Wang, Xiaoping Wang, Jing Zhu, Zhenqiang Wang, Ximu Zhang*, Kaiyong Cai, Jixi Zhang*. Combination wound healing using polymer entangled porous nanoadhesive hybrids with robust ROS scavenging and angiogenesis properties. Acta Biomaterialia 2022, 152, 171-185.

309. Rong Wang, Lingbin Che, Qian Feng *, Kaiyong Cai*. Tough, Flexible, and Bioactive Amphoteric Copolymer-based Hydrogel for Bone Regeneration without Encapsulation of Seed Cells and Simulating Cues. ACS Applied Materials & Interfaces 2022, 14, 12038−12049.

308. Yujia Wei, Maohua Chen, Dong wang, Menghuan Li, Yan Hu*, Zhong Luo*, Kaiyong Cai*. Aptamer/Hydroxyapatite-Functionalized Titanium Substrate Promotes Bone Defect Repair via Recruiting Mesenchymal Stem Cells. ACS Applied Materials & Interfaces 2022, 14, 42915-42930.

307. Jing Wu, Meng Li, Chuanchuan Lin, Pengfei Gao, Rui Zhang, Xuan Li, Jixi Zhang, Kaiyong Cai*. Moderated crevice corrosion susceptibility of Ti6Al4V implant material due to albumin-corrosion interaction . Journal of Materials Science & Technology 2022, 109, 209-220.

306. Zhenqiang Wang, Tao Ding, Liucan Wang, Shuai Wang, Meizhen Zhou, Kaiyong Cai, Jixi Zhang*. Exo/endogenous Factors Co-activatable Nanodevice for Spatiotemporally Controlled MiRNA Imaging and Guided Tumor Ablation. Nano Research 2022, 15,845-857.

305. Yulu Yang, Rui Chen, Ke Li, Pengfei Gao, Yi Gong, Weihu Yang*, Kaiyong Cai*. Design of manganese ion coated Prussian blue nanocarrier for the therapy of refractory diffuse large B-cell lymphoma based on a comprehensive analysis of ferroptosis regulators from clinical cases. Nano Research 2022 in press.

304. Lu Wang, Tingting Zhang, Yuxin Xing, Zhenqiang Wang, Xiyue Xie, Jixi Zhang*, Kaiyong Cai*. Interfacially responsive electron transfer and matter conversion by polydopamine mediated nanoplatforms for advancing disease theranostics. WIREs Nanomedicine & Nanobiotechnology 2022, 14, e1805.

303. Meizhen Zhou, Zhenqiang Wang, Daqing Xia, Xiyue Xie , Yuhua Chen, Yuxin Xing, Kaiyong Cai, Jixi Zhang*. Hybrid nanoassembly with two-tier host-guest architecture and regioselective enrichment capacity for repetitive SERS detection. Sensors and Actuators: B. Chemical 2022, 369, 132359.

302. Xu Zhang, Ye He, Xuan Li, Chuanchuan Lin, Zhang Yuan, Liangliang Dai, Feng Mae, Yi Lve, Tony Jun Huang, Mudan Ren*, Kaiyong Cai*, Shuixiang He*. Biocompatible, adhesive and stable GelMAc/PVAMA/MPDA@Cur hydrogel regulates immune response to improve endoscopic submucosal dissection-induced gastric ulcer healing in vivo. Applied Materials Today 2022, 28,101539.

301. Wenbo Geng†, Maowen Chen†, Bailong Tao, Rong Wang, Dong Wang, Ke Li, Chuanchuan Lin, Xuezhe Liu, Pengfei Gao, Zhong Luo*, Kaiyong Cai*. Cell-Free DNA Depletion via Cell-penetrating Poly(disulfide)s for Rheumatoid Arthritis Therapy. Applied Materials Today 2022, 26,10135.

300. Lu Wang, Genhua Liu, Yunping Hu, Shuangquan Gou, Tingting He, Qian Feng, and Kaiyong Cai*. Doxorubicin-loaded polypyrrole nanovesicles for suppressing tumor metastasis through combining photothermotherapy and lymphatic system-targeted chemotherapy. Nanoscale 2022,14, 3097-3111.

299. Jing Wu, Meng Li, Yang Zhou, Kun Xu, Xuan Li, Chuanchuan Lin, Jixi Zhang, Kaiyong Cai*. Pitting behavior of 316L stainless steel in direct culture with mesenchymal stem cells. Corrosion Science 2022, 204,110380.

298. Han Yang, Xiang Gu, Yan Li, Ke Zhang, Xihong Liu, Chengyao Huang, Yu Ren, Chao Qi*, Kaiyong Cai*. Multifunctional nanoreactors with nutrient consumption and ROS generation capabilities for antibacterial and skin repair. Journal of Materials Chemistry B 2022,10, 8664-8671.

297. Rui Zhang, Ye He, Bailong Tao, Jing Wu, Xinqiang Hu, Xuan Li, Zengzilu Xia*, Kaiyong Cai*. Multifunctional silicon calcium phosphate composite scaffolds promote stem cell recruitment and bone regeneration. Journal of Materials Chemistry B 2022, 10, 5218–5230.

296. Yile Jia, Xianhui Zhang, Weihu Yang*, Chuanchuan Lin, Bailong Tao, Zhiwen Deng, Pengfei Gao, Yulu Yang, Kaiyong Cai*. A pH-responsive hyaluronic acid hydrogel for regulating the inflammation and remodeling of the ECM in diabetic wounds. Journal of Materials Chemistry B 2022,10, 2875-2888.

295. Xiang Gu, Yan Li, Chao Qi*, Kaiyong Cai*. Biodegradable magnesium phosphates in biomedical applications. Journal of Materials Chemistry B 2022,10, 2097-2112.

294. Xinqiang Hu, Zengzilu Xia*, Kaiyong Cai*. Recent advances in 3D hydrogel culture systems for mesenchymal stem cell-based therapy and cell behavior regulation. Journal of Materials Chemistry B 2022,10, 1486-1507.

293. Tao Ding, Jing Zhu, Haidi Guan, Daqing Xia, Yuxin Xing, Jixi Huang, Zhenqiang Wang, Kaiyong Cai, Jixi Zhang*. Photothermally Triggered Melting and Perfusion: Responsive Colloidosomes for Cytosolic Delivery of Membrane-Impermeable Drugs in Tumor Therapy. Journal of Materials Chemistry B 2022,10, 1103-1115.

292. Yiding Shen, Kai Fang, Yun Xiang, Keyuan Xu, Liang Yu, Jiaquan Chen, Pingping Ma, Kaiyong Cai*, Xinkun Shen*, Jinsong Liu*. Improvement in osteogenesis, vascularization, and corrosion resistance of titanium with silicon-nitride doped micro-arc oxidation coatings. Frontiers in Bioengineering and Biotechnology 2022, 10, 1023032.

291. Yao Ding, Zhang Yuan, Jin-Wei Hu, Kun Xu, Hong Wang, Peng Liu*, Kai-Yong Cai*. Surface modification of titanium implants with micro-nanotopography and NIR photothermal property for treating bacterial infection and promoting osseointegration. Rare Metals 2022, 41(2) 673-688.

290. Jing Wu, Meng Li, Yang Zhou, Wenbo Geng, Xuan Li, Ke Li, Kun Xu, Yulu Yang, Pengfei Gao, Kaiyong Cai*. High-throughput fabrication of TiO2 nanotube arrays by 4-electrode bipolar electrochemistry. Scripta Materialia 2022, 221, 114947.  

289. Yanming Ma, Junjun Yang, Yan Hu, Zengzilu Xia*, Kaiyong Cai*. Osteogenic differentiation of the MSCs on silk fibroin hydrogel loaded Fe3O4@PAA NPs in static magnetic field environment. Colloids and Surfaces B: Biointerfaces 2022, 220, 112947.  

288. Hanyin Zhu, Yongyi Qu, Shuai Wang, Jixi Huang, Jing Zhu, Lu Wang*, Kaiyong Cai, Jixi Zhang*. Melanin Nanoparticle-Actuated Redox-State Perturbation and Temporally Photoactivated Thermal Stress for Synergistic Tumor Therapy. ACS Biomaterials Science & Engineering 2022, 8, 3944-3956.  

287. Yanming Ma, Xinqiang Hu, Shunbo Li, Ye He, Zengzilu Xia*, Kaiyong Cai*. A Facile and Flexible Humidity Sensor Based on Porous PDMS/AgNWs and GO for Environmental Humidity and Respiratory Detection. Macromolecular Materials and Engineering 2022,307, 2100686.  

286. Yehong Huo, Jian Hu, Yuanyuan Yin, Peng Liu, Kaiyong Cai, Wei Ji*. Self‐assembling peptide‐based functional biomaterials. ChemBioChem 2022, in press.

285. Yuehui Wang, Yuanyuan Yin, Sigal Rencus-Lazar, Kaiyong Cai, Ehud Gazit, Wei Ji*. Minimalistic Metabolite-Based Building Blocks for Supramolecular Functional Materials. ChemSystemsChem 2022, 4, e2022000.

2021

284. Chencheng Xue#, Menghuan Li#, Linawati Sutrisno, Beibei Yan, Yang Zhao, Yan Hu, Kaiyong Cai, Yanli Zhao, Shu-Hong Yu*, Zhong Luo*. Bioresorbable scaffolds with biocatalytic chemotherapy and in situ microenvironment modulation for postoperative tissue repair. Advanced Functional Materials 2021, 2008732.

283. Tao Ding, Zhenqiang Wang, Daqing Xia, Jing Zhu, Jixi Huang, Yuxin Xing, Shuai Wang, Yuhua Chen, Jixi Zhang*, Kaiyong Cai. Long-lasting reactive oxygen species generation by porous redox mediator-potentiated nanoreactor for effective tumor therapy. Advanced Functional Materials 2021, 2008573.

282. Jin Leng#, Ye He#, Zhang Yuan, Bailong Tao, Ke Li, Chuanchuan Lin, Kun Xu, Maowen Chen, Liangliang Dai, Xuemin Li, Tony Jun Huang, Kaiyong Cai*. Enzymatically-degradable hydrogel coatings on titanium for bacterial infection inhibition and enhanced soft tissue compatibility via a self-adaptive strategy. Bioactive Materials 2021,6, 4670-4685.

281. Chencheng Xue#, Menghuan Li#, Changhuang Liu#, Yanan Li, Yang Fei, Yan Hu, Kaiyong Cai, Yanli Zhao, Zhong Luo*. NIR-actuated remote activation of ferroptosis in target tumor cells through a photothermally responsive iron-chelated biopolymer nanoplatform. Angewandte Chemie International Edition 2021, 60, 8938-8947.

280. Bailong Tao, Chuanchuan Lin, Ye He, Zhang Yuan, Maowen Chen, Kun Xu, Kai Li, Ai Guo, Kaiyong Cai*, Lixue Chen*. Osteoimmunomodulation mediating improved osteointegration by OGP-loaded cobalt-metal organic framework on titanium implants with antibacterial property. Chemical Engineering Journal 2021,423, 130176.

279. Yulu Yang, Ju Liu, Maowen Chen, Pengfei Gao, Yi Gong, Rui Chen, Yu Tang, Weihu Yang*, Kaiyong Cai. Photolithographic-based stamp technique for improving the biocompatibility of antibacterial titanium implant by dynamic clearance of antibacterial agents. Chemical Engineering Journal 2021, 421, 129756.

278. Zhiwen Deng, Menghuan Li, Yan Hu*, Ye He, Bailong Tao, Zhang Yuan, Rong Wang, Maowen Chen, Zhong Luo*, Kaiyong Cai*. Injectable Biomimetic Hydrogels Encapsulating Gold/metal–organic frameworks Nanocomposites for Enhanced Antibacterial and Wound Healing Activity under Visible Light Actuation. Chemical Engineering Journal 2021, 420, 129668.

277. Bailong Tao, Chuanchuan Lin, Zhang Yuan, Ye He, Maowen Chen, Ke Li, Jingwei Hu, Yulu Yang, Zengzilu Xia*, Kaiyong Cai*. Near-infrared light controllable releasing platform of Gel-PDA@Cur composite hydrogel for promoting infected wound healing. Chemical Engineering Journal 2021, 403, 126182.

276. Wei Ji, Yiming Tang, Pandeeswar Makam, Yifei Yao, Ranran Jiao, Kaiyong Cai, Guanghong Wei*, Ehud Gazit*. Expanding the Structural Diversity and Functional Scope of Diphenylalanine-based Peptide Architectures by Hierarchical Co-Assembly. Journal of the American Chemical Society 2021, 143, 17633-17645.  

275. Xiyue Xie, Zhenqiang Wang, Meizhen Zhou, Yuxin Xing, Yuhua Chen, Jixi Huang, Kaiyong Cai, Jixi Zhang*. Redox Host–Guest Nanosensors Installed with DNA Gatekeepers for Immobilization-Free and Ratiometric Electrochemical Detection of miRNA. Small Method 2021, 5, 2101072.

274. Chuanchuan Lin, Ye He, Qian Feng, Kun Xu, Zhe Chen, Bailong Tao, Xuemin Li, Zengzilu Xia, Hong Jiang, Kaiyong Cai*. Self-renewal or Quiescence? Orchestrating the Fate of Mesenchymal Stem Cells by Matrix Viscoelasticity via PI3K/Akt-CDK1 Pathway. Biomaterials 2021, 279,121235.

273. Lu Lu, Kui Wang*, Chuanchuan Lin, Weihu Yang, Qiaojian Duan, Ke Li, Kaiyong Cai*. Constructing nanocomplexes by multicomponent self-assembly for curing orthotopic glioblastoma with synergistic chemo-photothermal therapy. Biomaterials 2021, 279, 121193.

272. Ye He#, Jin Leng#, Ke Li, Kun Xu, Chuanchuan Lin, Zhang Yuan, Rui Zhang, Danyang Wang, Bailong Tao, Tony Jun Huang, Kaiyong Cai*. A multifunctional hydrogel coating to direct fibroblast activation and infected wound healing via simultaneously controlled photobiomodulation and photodynamic therapies. Biomaterials 2021, 278, 121164.

271. Liangliang Dai*,#, Xiang Li#, Xinmin Zheng, Zhenxiang Fu, Mengjiao Yao, Siyu Meng, Jiangong Zhang, Binbin Han, Quanli Gao, Jing Chang, Kaiyong Cai*, Hui Yang*. TGF-β blockade-improved chemo-immunotherapy with pH/ROS cascade-responsive micelle via tumor microenvironment remodeling. Biomaterials 2021,276,121010.

270. Chencheng Xue, Linawati Sutrisno, Menghuan Li, Wei Zhu, Yang Fei, Changhuang Liu, Xuan Wang, Kaiyong Cai, Yan Hu*, Zhong Luo*. Implantable multifunctional black phosphorus nanoformulation-deposited biodegradable scaffold for combinational photothermal/chemotherapy and wound healing. Biomaterials 2021, 269, 120623.

269. Ke Li, Kun Xu, Ye He, Lu Lu, Yulan Mao, Pengfei Gao, Genhua Liu, Jing Wu, Yuchen Zhang, Yang, Xiang, Zhong Luo*, Kaiyong Cai*. Functionalized tumor-targeting nanosheets exhibiting Fe(II) overloading and GSH consumption for ferroptosis activation in liver tumor. Small 2021, 17, 2102046.

268. Ye He, Ke Li, Xin Yang, Jin Leng, Kun Xu, Zhang Yuan, Chuanchuan Lin, Bailong Tao, Xuan Li, Jingwei Hu, Liangliang Dai, Ryan Becker, Tony Jun Huang, Kaiyong Cai*. Calcium Peroxide Nanoparticles-embedded Coatings on Anti-inflammatory TiO2 Nanotubes for Bacteria Elimination and Inflammatory Environment Amelioration. Small 2021,17, 2102907.

267. Xuan Wang, Yuanyuan Zhao, Yan Hu, Yang Fei, Youbo Zhao, Chencheng Xue, Kaiyong Cai, Menghuan Li*, Zhong Luo*. Activatable Biomineralized Nanoplatform Remodels the Intracellular Environment of Multidrug-Resistant Tumors for Enhanced Ferroptosis/Apoptosis Therapy. Small 2021, 21, 2100130.

266. Zhang Yuan, Chuanchuan Lin, Liangliang Dai*, Ye He, Jingwei Hu, Kun Xu, Bailong Tao, Peng Liu*, Kaiyong Cai*. Near-Infrared Light-Activatable Dual-Action Nanoparticle Combats the Established Biofilms of Methicillin-Resistant Staphylococcus aureus and Its Accompanying Inflammation. Small 2021, 17, 2007522.

265. Xuan Wang, Youbo Zhao, Lei Shi, Yan Hu, Guanbin Song, Kaiyong Cai, Menghuan Li*, Zhong Luo*. Tumor-Targeted Disruption of Lactate Transport with Reactivity-Reversible Nanocatalysts to Amplify Oxidative Damage. Small 2021, 17, 2100130.

264. Junjie Liu#, Jinjin Shi#, Weimin Nie, Sijie Wang, Genhua Liu, Kaiyong Cai*. Recent Progress in the Development of Multifunctional Nanoplatform for Precise Tumor Phototherapy. Advanced Healthcare Materials 2021, 10, 2001207.

263. Xiyue Xie, Jia Tang, Yuxin Xing, Zhenqiang Wang, Tao Ding, Jixi Zhang*, Kaiyong Cai. Intervention of Polydopamine Assembly and Adhesion on Nanoscale Interfaces: State‐of‐the‐Art Designs and Biomedical Applications. Advanced Healthcare Materials 2021,10, 2002138.

262. Lu Lu, Genhua Liu, Chuanchuan Lin, Ke Li, Tingting He, Jixi Zhang, Zhong Luo*, Kaiyong Cai*. Mitochondrial Metabolism Targeted Nanoplatform for Efficient Triple-Negative Breast Cancer Combination Therapy. Advanced Healthcare Materials 2021, 10, 2100978.

261. Genhua Liu, Lu Wang, Ye He, Liucan Wang, Zhiwen Deng, Junjie Liu, Dan Peng, Tao Ding, Lu Lu, Yao Ding, Jixi Zhang, Peng Liu*, Kaiyong Cai*. Polydopamine nanosheets doped injectable hydrogel with nitric oxide release and photothermal effects for bacterial ablation and wound healing. Advanced Healthcare Materials 2021, 10, 202101476.

260. Mengnan Yang, Zhenqiang Wang, Tao Ding, Jia Tang, Xiyue Xie, Yuxin Xing, Lu Wang*, Jixi Zhang*, Kaiyong Cai. Interfacial Engineering of Hybrid Polydopamine/Polypyrrole Nanosheets with Narrow Band Gaps for Fluorescence Sensing of MicroRNA. ACS Applied Materials & Interfaces 2021, 13(35), 42183-42194.

259. Zhang Yuan, Ye He, Chuanchuan Lin, Peng Liu*, Kaiyong Cai*. Antibacterial Surface Design of Biomedical Titanium Materials for Orthopedic Applications. Journal of Materials Science & Technology  2021, 78, 51-67.

258. Zhenqiang Wang, Tao Ding, Liucan Wang, Shuai Wang, Meizhen Zhou, Kaiyong Cai, Jixi Zhang*. Exo/endogenous Factors Co-activatable Nanodevice for Spatiotemporally Controlled MiRNA Imaging and Guided Tumor Ablation. Nano Research 2021, 15, 847-857.

257. Maohua Chen, Yan Hu∗, Yanhua Hou, Yuting Sun, Maowen Chen, Menghuan Li, Lu Tan, Zhong Luo*, Kaiyong Cai*. Construction of a reactive oxygen species-responsive biomimetic multilayered titanium implant for in situ delivery of α-melanocyte-stimulating hormone to improve bone remolding in osteoporotic rats. Applied Materials Today 2021, 23, 101059.

256. Kun Xu, Zhang Yuan, Yao Ding, Ye He, Ke Li, Chuanchuan Lin, Bailong Tao, Yulu Yang, Xuan Li, Peng Liu*, Kaiyong Cai*. Near-infrared light triggered multi-mode synergetic therapy for improving antibacterial and osteogenic activity of titanium implants. Applied Materials Today 2021, 24, 101155.

255. Dan Peng,‡ Genhua Liu,‡ Ye He, Pengfei Gao, Shuangquan Gou, Jing Wu, Jinxiu Yu, Peng Liu* , Kaiyong Cai*. Fabrication of a pH-responsive core–shell nanosystem with a low-temperature photothermal therapy effect for treating bacterial biofilm infection. Biomaterials Science 2021, 9, 7483-7491.

254. Xingwei Ding, Wenyan Jiang, Lina Dong, Can Hong, Zhong Luo, Yan Hua, Kaiyong Cai*. Redox-responsive magnetic nanovectors self-assembled from amphiphilic polymer and iron oxide nanoparticles for a remotely targeted delivery of paclitaxel. Journal of Materials Chemistry B 2021,9, 6037-6043.

253. Maowen Chen#, Bailong Tao#, Yan Hu*, Menghuan Li, Maohua Chen, Lu Tan, Zhong Luo*, Kaiyong Cai*. Enhanced biocompatibility and osteogenic differentiation of mesenchymal stem cells of titanium by Sr–Ga clavate double hydroxides. Journal of Materials Chemistry B 2021,9, 6029-6036.

252. Rui Zeng#, Tingting He#, Lu Lu, Ke Li, Zhong Luo, Kaiyong Cai*. Ultra-thin metal-organic framework nanosheets for chemo-photodynamic synergistic therapy. Journal of Materials Chemistry B 2021, 9, 4143 - 4153.

251. Andri Kurniawan Sutanto, Yuxin Xing, Tao Ding, Zhenqiang Wang, Kaiyao Sun, Dong Mo, Jixi Zhang*, Kaiyong Cai. Hybrid mesoporous nanoparticles with highly integrated polydopamine for pH-responsive membrane permeation and drug delivery. Colloid and Interface Science Communications 2021, 41,100385.

250. Chuanchuan Lin, Ye He, Kun Xu, Qian Feng, Xuan Li, Songyue Zhang, Ke Li, Hong Jiang, Kaiyong Cai*. Mesenchymal stem cells resist mechanical confinement through the activation of cortex during cell division. ACS Biomaterials Science & Engineering 2021, 7, 4602-4613.

249. Yile Jia, Lu Qin, Yi Gong, Rui Chen, YuluYang, Weihu Yang*, Kaiyong Cai*. Experimental and theoretical investigations of the influences of one-dimensional hydroxyapatite nanostructures on cytocompatibility. Journal of Biomedical Materials Research Part A 2021, 109, 804–813.

248. Danyang Wang, Lu Qin, Weihu Yang*, Ye He, Songyue Zhang, Yulu Yang, Kun Xu, Pengfei Gao, Jinxiu Yu, Kaiyong Cai*. A Conductive Hydrogel Based on GaIn and PVA/PAA/Fe3+ for Strain Sensor and Physiological Signal Detection. ACS Applied Polymer Materials 2021, 3, 52685276.

2020

247. Chen-Cheng Xue#, Meng-Huan Li#, Yang Zhao#, Jun Zhou, Yan Hu, Kai-Yong Cai, Yanli Zhao, Shu-Hong Yu*, Zhong Luo*. Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells. Science Advance 2020, 6, eaax1346.

246. Ke Li, Chuanchuan Lin, Ye He, Lu Lu, Kun Xu, Bailong Tao, Zengzilu Xia, Rui Zeng, Yulan Mao, Zhong Luo*, Kaiyong Cai*. Engineering of Cascade-Responsive Nanoplatform to Inhibit Lactate Efflux for Enhanced Tumor Chemo-Immunotherapy. ACS Nano 2020, 14, 10, 14164–14180.

245. Zhang Yuan, Chuanchuan Lin, Ye He, Bailong Tao, Maowen Chen, Jixi Zhang, Peng Liu*, Kaiyong Cai*. Near Infrared Light Triggered Nitric Oxide-Enhanced Photodynamic Therapy and Low-Temperature Photothermal Therapy for Biofilm Elimination. ACS Nano 2020, 14, 3, 3546-3562.

244. Xuan Wang, Menghuan Li, Yanhua Hou, Yanan Li, Xuemei Yao, Chencheng Xue, Yang Fei, Yang Xiang, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Tumor‐Microenvironment‐Activated In Situ Self‐Assembly of Sequentially Responsive Biopolymer for Targeted Photodynamic Therapy. Advanced Functional Materials 2020, 2000229.

243. Youbo Zhao, Menghuan Li, Xuemei Yao, Yang Fei, Zhenghong Lin, Zhengguo Li, Kaiyong Cai, Yanli Zhao, Zhong Luo*. HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications. Cell Reports 2020, 33, 108487.

242. Lu Lu, Xiaojing Zhao, Tiwei Fu, Ke Li, Ye He, Zhong Luo*, Liangliang Dai, Rui Zeng, Kaiyong Cai*. An iRGD-conjugated prodrug micelle with blood-brain-barrier penetrability for anti-glioma therapy. Biomaterials 2020, 230, 119666.

241. Liangliang Dai, Xiang Li, Mengjiao Yao, Peiyun Niu, Xichen Yuan, Ke Li, Maowen Chen, Zengxiang Fu, Xianglong Duan, Haibin Liu, Kaiyong Cai*, Hui Yang*. Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy. Biomaterials 2020, 241, 119901.

240. Lu Wang, Ye He, Tingting He, Genhua Liu, Chuanchua Lin, Ke Li, Lu Lu, Kaiyong Cai*. Lymph node-targeted immune-activation mediated by imiquimod-loaded mesoporous polydopamine based-nanocarriers. Biomaterials 2020, 255, 120208.

239. Xuemei Yao, Menghuan Li, Bing Li, Chencheng Xue, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Tumor-targeted upconverting nanoplatform constructed by host-guest interaction for near-infrared-light-actuated synergistic photodynamic-/ chemotherapy. Chemical Engineering Journal 2020, 390, 124516.

238. Bailong Tao, Chuanchuan Lin, Zhang Yuan, Ye He, Lu Lu, Maowen Chen, Yao Ding, Yulu Yang, Zengzilu Xia*, Kaiyong Cai*. Surface modification of titanium implants by ZIF-8@Levo/LBL coating for inhibition of bacterial-associated infection and enhancement of in vivo osseointegration. Chemical Engineering Journal 2020,390,124621.

237. Ye He#, Kun Xu#, Ke Li, Zhang Yuan, Yao Ding, Maowen Chen, Chuanchuan Lin, Bailong Tao, Xuemin Li, Guanjun Zhang, Peng Liu*, Kaiyong Cai*. Improved osteointegration by SEW2871-encapsulated multilayers on micro-structured titanium via macrophages recruitment and immunomodulation. Applied Materials Today 2020, 20, 100673.

236. Caiyun Mu , Ye He , Yan Hu*, Menghuan Li, Maowen Chen, Rong Wang, Yang Xiang , Zhong Luo*, Kaiyong Cai*.Construction of chemokine substance P-embedded biomimetic multilayer onto bioactive magnesium silicate-titanium implant for bone regeneration. Applied Materials Today 2020, 20, 100777.

235. Menghuan Li, Hui Zhang, Yanhua Hou, Xuan Wang, Chencheng Xue, Wei Li, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. State-of-the-art iron-based nanozymes for biocatalytic tumor therapy. Nanoscale Horizons 2020, 5, 202-217.

234. Jinghua Li, Xiaonan Li, Gaofeng Liang, Jianfeng Bao, Changshun Ruan*, Kaiyong Cai*. ROS Self-Generation and Hypoxia Self-Enhanced Biodegradable Magnetic Nanotheranostics for Targeted Tumor Therapy. Nanoscale Horizons 2020, 5, 350-358.

233. Genhua Liu, Liucan Wang, Junjie Liu, Lu Lu, Dong Mo, Ke Li, Xin Yang, Rui Zeng, Jixi Zhang, Peng Liu*, Kaiyong Cai*.Engineering of a core-shell nanoplatform overcoming multidrug resistance via starvation-enhanced chemotherapy. Advanced Healthcare Materials 2020, 9, 2000432.

232. Maohua Chen, Ling Huang, Xinkun Shen, Menghuan Li, Zhong Luo, Kaiyong Cai, Yan Hu*. Construction of multilayered molecular reservoirs on a titanium alloy implant for combinational drug delivery to promote osseointegration in osteoporotic conditions. Acta Biomaterialia 2020, 105, 304-318.

231. Yang Fei, Menghuan Li, Yanan Li, Xuan Wang, Chencheng Xue, Zuosu Wu, Jiaying Xu, Zilu Xiazeng*, Kaiyong Cai*, Zhong Luo*. Hierarchical integration of degradable mesoporous silica nanoreservoirs and supramolecular dendrimer complex as a general-purpose tumor-targeted biomimetic nanoplatform for gene/small-molecule anticancer drug co-delivery. Nanoscale 2020, 30, 16102-16112.

230. Ke Li, Lu Lu, Chencheng Xue, Ju Liu, Ye He, Jun Zhou, Zengzilu Xia, Liangliang Dai*, Zhong Luo*, Yulan Mao, Kaiyong Cai*. Polarization of Tumor-Associated Macrophages Phenotype via Porous Hollow Iron Nanoparticles for Tumor Immunotherapy in vivo. Nanoscale 2020, 12, 130–144.

229. Yao Ding#, Yansha Hao#, Zhang Yuan, Bailong Tao, Maowen Chen, Chuanchuan Lin, Peng Liu*, Kaiyong Cai*. A dual-functional implant with enzyme-responsive effect for bacterial infection therapy and tissue regeneration. Biomaterials Science 2020, 8, 1840-1854.

228. Chuanchuan Lin, Kun Xu, Ye He, Bailong Tao, Zhang Yuan, Ke Li, Xuemin Li, Zengzilu Xia*, Kaiyong Cai*. Dynamic Matrix Potentiate Mesenchymal Stromal Cells Paracrine via Effective Mechanical Dose. Biomaterials Science 2020, 8, 4779-4791.

227. Yao Ding, Zhang Yuan, Peng Liu*, Kaiyong Cai*, Ruirui Liu. Fabrication of strontium-incorporated protein supramolecular nanofilm on titanium substrates for promoting osteogenesis. Materials Science & Engineering C 2020, 111, 110851.

226 Yonglin Yu, Qichun Ran, Xinkun Shen, Hong Zheng*, Kaiyong Cai*. Enzyme responsive titanium substrates with antibacterial property and osteo/angio-genic differentiation potentials. Colloids and Surface B 2020, 185, 110592.

225. Maowen Chen, Yan Hu*, Yanhua Hou, Menghuan Li, Maohua Chen, Lu Tan, Caiyun Mu, Bailong Tao, Zhong Luo*, Kaiyong Cai*. Osteogenesis regulation of mesenchymal stem cells via autophagy induced by silica–titanium composite surfaces with different mechanical moduli. Journal of Materials Chemistry B 2020,8, 9314-9324.

224. Caiyun Mu, Yan Hu*, Yanhua Hou, Menghuan Li, Ye He, Xinkun Shen, Bailong Tao, Chuanchuan Lin, Maowen Chen, Maohua Chen, Kaiyong Cai*. Substance P-embedded multilayer on titanium substrates promotes local osseointegration via MSC recruitment. Journal of Materials Chemistry B 2020,8, 1212-1222.

223. Songyue Zhang, Shunbo Li, Zengzilu Xia*, Kaiyong Cai*. A Review of Electronic Skin: Soft Electronics and Sensors to Human Health. Journal of Materials Chemistry B 2020,8, 852-862.

222. Lu Tan, Yan Hu*, Yanhua Hou, Maowen Chen, Chencheng Xue,Maohua Chen, Yuting Sun, Caiyun Mu, Zhong Luo*, Kaiyong Cai*. Osteogenic differentiation of mesenchymal stem cells by silica/calcium micro-galvanic effects on the titanium surface. Journal of Materials Chemistry B 2020, 8, 2286-2295.

221. Genhua Liu#, Huining Liang#, Ye He, Lu Lu, Lu Wang, Peng Liu*, Kaiyong Cai*. A nanoplatform based on mesoporous silica-coated gold nanorods for cancer triplex therapy. Journal of Materials Chemistry B 2020, 8, 9686--9696.

220. Lu Lu, Bing Li, Chuanchuan Lin, Ke Li, Genhua Liu, Zengzilu Xia, Zhong Luo*, Kaiyong Cai*. Redox-responsive amphiphilic camptothecin prodrug nanoparticles for targeted liver tumor therapy. Journal of Materials Chemistry B 2020, 8, 3918-3928.

219. Dong Mo, Zhengqiang Wang, Kaiyao Sun, Xiyue Xie, Jixi Zhang*, Kaiyong Cai*. Core–shell metal–organic frameworks and hierarchical host–guest structures toward water-stable luminescence of lanthanide complexes in encoding beads. Journal of Materials Chemistry C, 2020,8, 11110-11118.

218. Kui Xu*, Mi Zhou, Ming Li, Weizhen Chen, Yabin Zhu, Kaiyong Cai. Metal-phenolic networks as a promising platform for pH-controlled release of bioactive divalent metal ions. Applied Surface Science 2020, 511, 145569.

217. Jia Tang, Yuxin Xing, Zhenqiang Wang, Mengnan Yang, Jixi Zhang*, Kaiyong Cai*. Janus nanoparticles with asymmetrically subcompartmentalized sensing and amplification modules toward fluorescence detection of microRNA. Sensors and Actuators: B. Chemical 2020, 320, 128438.

216. Wei Zhang*, Nemat O. Keyhani, Hao Zhang, Kaiyong Cai, Yuxian Xia*. Inhibitor of apoptosis-1 gene as a potential target for pest control and its involvement in immune regulation during fungal infection. Pest Management Science 2020, 76, 1831-1840.

215. Yulu Yang, Bailong Tao, Ti Gong, Rui Chen, Weihu Yang*, Chuanchuan Lin, Maowen Chen, Lu Qin, Yile Jia, Kaiyong Cai*. Functionalization of Ti substrate with pH‐responsive naringin‐ZnO nanoparticles for the reconstruction of large bony after osteosarcoma resection. Journal of Biomedical Materials Research Part A 2020,108, 2190-2205.

214. Ke Li, Menghuan Li, Zhong Luo*, Yulan Mao, Yonglin Yu, Ye He, Jun Zhou, Yang Fei, Yuxia Pei, Kaiyong Cai*. Overcoming the hypoxia-induced drug resistance in liver tumor by the concurrent use of apigenin and paclitaxel. Biochemical and Biophysical Research Communications 2020, 526, 321-327.

213. Wei Zhang, Xiaoli Zheng, Jianhong Chen, Nemat O. Keyhani, Kaiyong Cai, Yuxian Xia*. Spatial and temporal transcriptomic analyses reveal locust initiation of immune responses to Metarhizium acridum at the pre-penetration stage. Developmental and Comparative Immunology 2020, 104, 103524.

2019年

212. Liangliang Dai, Xiang Li, Xianglong Duan, Menghuan Li, Peiyun Niu, Huiyun Xu, Kaiyong Cai*, Hui Yang*. A pH/ROS Cascade-Responsive Charge-Reversal Nanosystem with Self-Amplified Drug Release for Synergistic Oxidation-Chemotherapy. Advanced Science 2019, 6, 1801807.

211. Xinkun Shen, Yangyang Zhang, Pingping Ma, Linawati Sutrisno, Zhong Luo, Yan Hu, Yonglin Yu, Bailong Tao, Chuanqiang Li*, Kaiyong Cai*. Fabrication of magnesium/zinc-metal organic framework on titanium implants to inhibit bacterial infection and promote bone regeneration. Biomaterials 2019, 212, 1-16.

210. Jun Zhou, Chencheng Xue, Yanhua Hou, Menghuan Li*, Yan Hu, Qiufang Chen, Yanan Li, Ke Li, Guanbin Song, Kaiyong Cai*, Zhong Luo*. Oxygenated theranostic nanoplatforms with intracellular agglomeration behavior for improving the treatment efficacy of hypoxic tumors. Biomaterials 2019, 197, 129-145.

209. Zhang Yuan, Bailong Tao, Ye He, Ju Liu, Chuanchuan Lin, Xinkun Shen, Yao Ding, Yonglin Yu, Caiyun Mu, Peng Liu*, Kaiyong Cai*. Biocompatible MoS2/PDA-RGD coating on titanium implant with antibacterial property via intrinsic ROS-independent oxidative stress and NIR irradiation. Biomaterials 2019, 217, 119290.

208. Chuanchuan Lin, Bailong Tao, Yiman Deng, Ye He, Xinkun Shen, Rong Wang, Lu Lu, Zhihong Peng, Zengzilu Xia*, Kaiyong Cai*. Matrix Promote Mesenchymal Stromal Cell Migration with Improved Deformation via Nuclear Stiffness Decrease. Biomaterials 2019, 217,119300.

207. Zhang Yuan, Bailong Tao, Ye He, Caiyun Mu, Genhua Liu, Jixi Zhang, Peng Liu*, Kaiyong Cai*. Remote Eradication of Biofilm on Titanium Implant via Near-Infrared Light Triggered Photothermal/Photodynamic Therapy Strategy. Biomaterials 2019, 223, 119479.

206. Zhenqiang Wang, Liucan Wang, Neeraj Prabhakar, Yuxin Xing, Jessica M. Rosenholm, Jixi Zhang*, Kaiyong Cai. CaP coated mesoporous polydopamine nanoparticles with responsive membrane permeation ability for combined photothermal and siRNA therapy. Acta Biomaterialia 2019, 86, 416-428.

205. Tao Ding, Yuxin Xing, Zhenqiang Wang, Haidi Guan, Liucan Wang, Jixi Zhang*, Kaiyong Cai. Structural complementarity from DNA for directing two-dimensional polydopamine nanomaterials with biomedical applications. Nanoscale Horizons 2019, 4, 652-657.

204. Haidi Guan, Tao Ding, Wei Zhou, Zhenqiang Wang, Jixi Zhang*, Kaiyong Cai. Hexagonal polypyrrole nanosheets from interface driven heterogeneous hybridization and self-assembly for photothermal cancer treatment. Chemical Communications 2019, 55, 4359-4362.

203. Ju Liu, Yu Tang, Weihu Yang*, Bailong Tao, Ye He, Xinkun Shen, Tingting Shen, Chuanchuan Lin, Kaiyong Cai*. Functionalization of titanium substrate with multifunctional peptide OGP-NAC for the regulation of osteoimmunology. Biomaterials Science 2019, 7, 1463-1476.

202. Ye He#, Xin Yang#, Zhang Yuan, Xinkun Shen, Kun Xu, Chuanchuan Lin, Bailong Tao, Ke Li, Maowen Chen, Yan Hu, Zhong Luo, Zengzilu Xia*, Kaiyong Cai*. Regulation of MSCs and macrophages functions in bone healing process by peptide LL-37-loaded silk fibroin nanoparticles on titanium surface. Biomaterials Science 2019,7, 5492 - 5505.

201. Ziyang Jin, Xufeng Yan, Ke Shen, Xingtang Fang, Chunlei Zhang, Qinglei Ming, Min Lai*, Kaiyong Cai*. TiO2 nanotubes promote osteogenic differentiation of mesenchymal stem cells via regulation of lncRNA CCL3-AS. Colloids and Surface B 2019, 181,416-425.

200. Xinkun Shen, Hao Gu, Pingping Ma, Zhong Luo, Menghuan Li, Yan Hu*, Kaiyong Cai*. Minocycline-incorporated multilayers on titanium substrates for simultaneous regulation of MSCs and macrophages. Materials Science & Engineering C 2019, 102, 696-707.

199. Maowen Chen, Yan Hu*, Yan-Hua Hou, Menghuan Li, Maohua Chen, Caiyun Mu, Bailong Tao, Wei Zhu, Zhong Luo and Kaiyong Cai*. Differentiation regulation of mesenchymal stem cells via autophagy induced by structurally-different silica based nanobiomaterials. Journal of Materials Chemistry B 2019, 7, 2657-2666.

198. Bailong Tao, Chuanchuan Lin, Zhang Yuan, Xinkun Shen, Ju Liu, Maowen Chen, Ye He, Yangyang Zhang, Zhihong Peng, Yan Hu, Kaiyong Cai*. Copper-nanoparticle- embedded hydrogel for killing bacteria and promoting wound healing with photothermal therapy. Journal of Materials Chemistry B 2019, 7, 2534-2548.

197. Lu Lu, Xinkun Shen, Bailong Tao, Chuanchuan Lin, Ke Li, Zhong Luo, Kaiyong Cai*. The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas. Journal of Materials Chemistry B 2019, 7, 2054-2062.

196. Bailong Tao, Yiman Deng, Liying Song, Wenwen Ma, Ying Qian, Chuanchuan Lin, Zhang Yuan, Lu Lu, Maowen Chen, Xin Yang, Kaiyong Cai*. BMP2-loaded titania nanotubes coating with pH-responsive multilayers for bacterial infections inhibition and osteogenic activity improvement. Colloids and Surface B 2019, 177, 242-252.

195. Maohua Chen, Yan Hu*, Menghuan Li, Maowen Chen, Xinkun Shen, Zhong Luo, Caiyun Mu, Weihu Yang, Peng Liu, Kaiyong Cai*. Regulation of osteoblast differentiation by osteocytes cultured on sclerostin antibody conjugated TiO2 nanotube array. Colloids and Surface B 2019, 175, 663-670.

194. Xinkun Shen#, Yonglin Yu#, Pingping Ma*, Zhong Luo, Yan Hu, Menghuan Li, Ye He, Yangyang Zhang, Zhihong Peng, Guanbin Song, Kaiyong Cai*. Titania nanotubes promote osteogenesis via mediating crosstalk between macrophages and MSCs under oxidative stress. Colloids and Surface B 2019, 180, 39-48.

193. Kui Xu*, Weizhen Chen, Guanglei Fu, Xianbo Mou, Ruixia Hou, Yabin Zhu*, Kaiyong Cai*. In situ self-assembly of graphene oxide/polydopamine/Sr2+ nanosheets on titanium surfaces for enhanced osteogenic differentiation of mesenchymal stem cells. Carbon 2019, 142, 567-579.

192. Jixi Huang, Shuai Wang, Yuxin Xing, Wei Zhou, Jixi Zhang*Kaiyong Cai. Interface-Hybridization-Enhanced Photothermal Performance of Polypyrrole/Polydopamine Heterojunctions on Porous Nanoparticles. Macromolecular Rapid Communications 2019, 40, 1900263.

191. Bailong Tao, Maowen Chen, Chuanchuan Lin, Lu Lu, Zhang Yuan, Ju Liu, Qiang Liao, Zengzilu Xia*, Zhihong Peng*, Kaiyong Cai*. Zn-incorporation with graphene oxide on Ti substrates surface to improve osteogenic activity and inhibit bacterial adhesion. Journal of Biomedical Materials Research Part A 2019, 107A, 2310-2326.

190. Youbo Zhao, Wei Li, Menghuan Li*, Yan Hu, Hui Zhang, Guanbin Song, Li Yang, Kaiyong Cai, Zhong Luo*. Targeted inhibition of MCT4 disrupts intracellular pH homeostasis and confers self-regulated apoptosis on hepatocellular carcinoma. Experimental Cell Research 2019, 384, 111591.

189. Menghuan Li, Zhong Luo*, Zhihong Peng, Kaiyong Cai*. Cascade- amplification of therapeutic efficacy: An emerging opportunity in cancer treatment. WIREs Nanomedicine & Nanobiotechnology 2019, 11, e1555.

188. Wei-Ke Xu, Jing-Yu Tang, Zhang Yuan, Cai-Yun Cai, Xiao-Bin Chen, Shu-Quan Cui, Peng Liu, Lin YuKai-Yong Cai, Jian-Dong Ding. Accelerated Cutaneous Wound Healing Using an Injectable Teicoplanin-loaded PLGA-PEG-PLGA Thermogel Dressing. Chinese Journal of Polymer Science 2019, 37(6), 548-559.

187. Kui Xu*, Kaiyong Cai. Self-assembled phase-transited lysozyme/heparin coating on titanium surfaces for improved hemocompatibility. Materials Letters 2019, 247, 95-108.

186. Yangyang Zhang, Xinkun Shen*, Pingping Ma, Kaiyong Cai*. Composite coatings of Mg-MOF74 and Sr-substituted hydroxyapatite on titanium substrates for local antibacterial, anti-osteosarcoma and pro-osteogenesis applications. Materials Letters 2019, 241, 18-22.

185. Kai Li, Kaiyong Cai, Qichun Ran*, Dianming Jiang*. Biomimetic triphase composite scaffolds with antibacterial and anti-tumor potentials for bone repair. Materials Letters 2019, 256, 126590.

184. 王蓉,沈新坤,胡燕,蔡开勇*;医用材料表界面设计及其与细胞相互作用。高分子学报, 2019, 9, 863-872.

2018年

183. Liangliang Dai, Ke Li, Menghuan Li, Xiaojing Zhao, Zhong Luo, Lu Lu, Yanfeng Luo, Kaiyong Cai*. Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration. Advanced Functional Materials 2018, 28, 1707249.

182. Jun Zhou, Menghuan Li, Zhong Luo*, Qiufang Chen, Hexu Cao, Runlan Huo, Chencheng Xue, Linawati Sutrisno, Lan Hao, Yang Cao, Haitao Ran, Lu Lu, Ke Li, Kaiyong Cai*. Engineering of a Nanosized Biocatalyst for Combined Tumor Starvation and Low-temperature Photothermal Therapy. ACS Nano 2018,12, 2858-2872.

181. Yuna Qian, Linhao Li*, Yang Song, Lili Dong, Peixing Chen, Xiaoming Li, Kaiyong Cai, Oliver Germershaus, Li Yang*, Yubo Fan*. Surface modification of nanofibrous matrices via layer-by-layer functionalized silk assembly for mitigating the foreign body reaction. Biomaterials 2018, 164, 22-37.

180. Manping Lin, Shilong Mao, Jinfeng Wang, Juan Xing, Yuanliang Wang, Kaiyong Cai, Yanfeng Luo*. Adsorption force of fibronectin controls transmission of cell traction force and subsequent stem cell fate. Biomaterials 2018, 162, 170-182.

179. Junjie Liu, Huining Liang, Menghuan Li, Zhong Luo, Jixi Zhang, Xingming Guo, Kaiyong Cai*. Tumor acidity activated multifunctional nanoplatform for NIR-mediated multiple enhanced photodynamic and photothermal tumor therapy. Biomaterials 2018, 157, 107-124.

178. Yonglin Yu, Xinkun Shen*, Zhong Luo, Yan Hu, Menghuan Li, Pingping Ma, Qichun Ran, Liangliang Dai, Ye He, Kaiyong Cai*. Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment. Biomaterials 2018, 167, 44-57.

177. Jun Zhou, Menghuan Li, Wei Qi Lim, Zhong Luo, Soo Zeng Fiona Phua, Runlan Huo, Liqi Li, Ke Li, Liangliang Dai, Junjie Liu, Kaiyong Cai, Yanli Zhao. A Transferrin-Conjugated Hollow Nanoplatform for Redox- Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions. Theranostics 2018, 8(2), 518-532.

176. Jinghua Li, Xiangyang Zu, Gaofeng Liang, KeKe Zhang, Yuliang Liu*, Ke Li, Zhong Luo, Kaiyong Cai*. Octopod PtCu Nanoframe as Multifunctional Theranostic Nanoplatform for Dual-Modal Imaging-Guided Synergistic Photothermal Radiotherapy. Theranostics 2018, 8(4), 1042-1058.

175. Conghui Deng, Xinkun Shen, Weihu Yang*, Zhong Luo, Pingping Ma, Tingting Shen, Ju Liu, Kaiyong Cai*. Construction of zinc-incorporated nano-network structures on a biomedical titanium surface to enhance bioactivity. Applied Surface Science 2018, 453, 263–270.

174. Weizhen Chen, Kui Xu, Bailong Tao, Liangliang Dai, Yonglin Yu, Caiyun Mu, Xinkun Shen, Yan Hu, Ye He, Kaiyong Cai*. Multilayered coating of titanium implants promotes coupled osteogenesis and angiogenesis in vitro and in vivo. Acta Biomaterialia 2018,74,489-504.

173. Ye He, Caiyun Mu, Xinkun Shen, Zhang Yuan, Ju Liu, Weizhen Chen, Chuanchuan Lin, Bailong Tao, Bin Liu, Kaiyong Cai*. Peptide LL-37 coating on micro-structured titanium implants to facilitate bone formation in vivo via mesenchymal stem cells recruitment. Acta Biomaterialia 2018, 80, 412-424.

172. Tingting Shen, Weihu Yang*, Xinkun Shen, Weizhen Chen, Bailong Tao, Xiaoqing Yang, Jianping Yuan, Peng Liu, Kaiyong Cai*. Polydopamine-assisted Hydroxyapatite and Lactoferrin Multilayer on Titanium for Regulating Bone Balance and Enhancing Antibacterial Property. ACS Biomaterials Science & Engineering 2018 4 (9), 3211–3223.

171. Caiyun Mu, Yan Hu*, Ling Huang, Xinkun Shen, Menghuan Li, Liqi Li, Hao Gu, Yonglin Yu, Zhining Xia, Kaiyong Cai*. Sustained raloxifene release from hyaluronan alendronate-functionalized titanium nanotube arrays capable of enhancing osseointegration in osteoporotic rabbits. Materials Science and Engineering: C 2018, 82, 345-353.

170. Linawati Sutrisno, Yan Hu*, Xinkun Shen, Menghuan Li, Zhong Luo, Liangliang Dai, Sixiang Wang, Julia Li Zhong, Kaiyong Cai*. Fabrication of hyaluronidase-responsive biocompatible multilayers on BMP2 loaded titanium nanotube for the bacterial infection prevention. Materials Science and Engineering: C 2018, 89, 95-105.

169. Qichun Ran, Yonglin Yu, Weizhen Chen, Xinkun Shen, Caiyun Mu, Zhang Yuan, Bailong Tao, Yan Hu, Weihu Yang*, Kaiyong Cai*. Deferoxamine loaded titania nanotubes substrates regulate osteogenic and angiogenic differentiation of MSCs via activation of HIF-1α signaling. Materials Science and Engineering: C 2018, 91, 44-54.

168. Yuxia Pei, Menghuan Li, Yanhua Hou, Yan Hu*, Guangyu Chu, Liangliang Dai, Ke Li, Yuxin Xing, Bailong Tao, Yonglin Yu, Chencheng Xue, Ye He, Zhong Luo, Kaiyong Cai*. An autonomous tumor-targeted nanoprodrug for reactive oxygen species-activatable dual-cytochrome c/doxorubicin antitumor therapy. Nanoscale 2018,10, 11418-11429.

167. Junjie Liu, Xingming Guo*, Zhong Luo, Jixi Zhang, Menghuan Li, Kaiyong Cai*. Hierarchically stimuli-responsive nanovectors for improved tumor penetration and programed tumor therapy. Nanoscale 2018, 10, 13737–13750.

166. Yonglin Yu, Xinkun Shen, Junjie Liu, Yan Hu, Qichun Ran, Caiyun Mu, Kaiyong Cai*. Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop. Colloids and Surface B-Biointerfaces 2018, 170, 1-10.

165. Ye He, Yangyang Zhang, Xinkun Shen, Bailong Tao, Ju Liu, Zhang Yuan, Kaiyong Cai*. The fabrication and in vitro properties of antibacterial polydopamine-LL-37-POPC coatings on micro-arc oxidized titanium. Colloids and Surface B-Biointerfaces 2018, 170, 54-63.

164. Bailong Tao, Xinkun Shen, Zhang Yuan, Qichun Ran, Tingting Shen, Yuxia Pei, Ju Liu, Ye He, Yan Hu, Kaiyong Cai*. N‑halamine-based multilayers on titanium substrates for antibacterial application. Colloids and Surface B-Biointerfaces 2018, 170, 382-392.

163. Zhang Yuan, Peng Liu*, Yansha Hao, Yao Ding, Kaiyong Cai*. Construction of Ag-incorporated coating on Ti substrates for inhibited bacterial growth and enhanced osteoblast response. Colloids and Surface B-Biointerfaces 2018, 171, 597-605.

162. Haidi Guan, Liucan Wang, Jixi Zhang*, Yuxin Xing, Kaiyong Cai. Selective Enrichment of Polydopamine in Mesoporous Nanocarriers for Nuclear-Targeted Drug Delivery. Particle & Particle Systems Characterization 2018, 35(6) 1800011.

161. Linawati Sutrisno, Sixiang Wang, Menghuan Li, Zhong Luo, Chunli Wang, Tingting Shen, Peixing Chen, Li Yang, Yan Hu*, Kaiyong Cai*. Construction of three-dimensional net-like polyelectrolyte multilayered nanostructures onto titanium substrates for combined antibacterial and antioxidant applications. Journal of Materials Chemistry B 2018, 6, 5290-5302.

160. Tao Ding, Liucan Wang, Jixi Zhang*, Yuxin Xing, Kaiyong Cai. Interface active polydopamine for nanoparticles stabilized nanocapsules in a one-pot assembly strategy toward efficient drug delivery. Journal of Materials Chemistry B 2018, 6, 1754-1763.

159. Zhang Yuan, Peng Liu*, Yanan Liang, Bailong Tao, Ye He, Yansha Hao, Weihu Yang, Yan Hu, Kaiyong Cai*. Investigation of osteogenic responses of Fe-incorporated micro/nano-hierarchical structure on titanium surface. Journal of Materials Chemistry B 2018, 6, 1359-1372.

158. Zhang Yuan, Suzhou Huang, Shaoxiong Lan, Haizhou Xiong, Bailong Tao, Yao Ding, Yisi Liu, Peng Liu*, Kaiyong Cai*. Surface engineering of titanium implants with enzyme-triggered antibacterial property and enhanced osseointegration in vivo. Journal of Materials Chemistry B 2018, 8, 8090-8104.

157. Liucan Wang, Haidi Guan, Zhenqiang Wang, Yuxin Xing, Jixi Zhang*, Kaiyong Cai. Hybrid Mesoporous–Microporous Nanocarriers for Overcoming Multidrug Resistance by Sequential Drug Delivery. Molecular Pharmaceutics2018, 15(7), 2503–2512.

156. Weizhen Chen, Wen Li, Kui Xu, Menghuan Li, Liangliang Dai, Xinkun Shen, Yan Hu, Kaiyong Cai*. Functionalizing titanium surface with PAMAM-dendrimers and human BMP2 gene via layer-by-layer assembly for enhanced osteogenesis. Journal of Biomedical Materials Research Part A 2018, 106(3), 706-717.

155. Ju Liu, Weihu Yang*, Bailong Tao, Tingting Shen, Ye He, Xinkun Shen, Kaiyong Cai*. Preparing and immobilizing antimicrobial osteogenic growth peptide on titanium substrate surface. Journal of Biomedical Materials Research Part A 2018, 106A: 3021–3033.

154. Qichun Ran, Weihu Yang*, Yan Hu, Xinkun Shen, Yonglin Yu, Yang Xiang, Kaiyong Cai*. Osteogenesis of 3D printed porous Ti6Al4V implants with different pore sizes. Journal of the Mechanical Behavior of Biomedical Materials 2018,84,1-11.

153. Peng Liu*, Yansha Hao, Yao Ding, Zhang Yuan, Yisi Liu, Kaiyong Cai*, Fabrication of enzyme-responsive composite coating for the design of antibacterial surface. Journal of Materials Science: Materials in Medicine 2018,29,160-168.

152. Jinhua Li*, Xiaonan Li, Wenpo Feng, Lu Huang, Yan Zhao, Yan Hu, Kaiyong Cai*. Octopus-like PtCu nanoframe as peroxidase mimic for phenol removal. Materials Letters 2018, 229, 193–197.

2017年

151. Junjie Liu, Menghuan Li, Zhong Luo, Liangliang Dai, Xingming Guo, Kaiyong Cai*. Design of nanocarriers based on complex biological barriers in vivo for tumor therapy. Nano Today 2017, 15, 56-90.

150. Menghuan Li, Zhong Luo*, Zhining Xia, Xinkun Shen, Kaiyong Cai*. Time-sequenced drug delivery approaches towards effective chemotherapeutic treatment of glioma. Materials Horizons 2017, 4, 977-996.

149. Weizhen Chen, Xinkun Shen,Yan Hu, Kui Xu, Qichun Ran, Yonglin Yu, Liangliang Dai, Zhang Yuan, Ling Huang, Tingting Shen, Kaiyong Cai*. Surface functionalization of titanium implants with chitosan-catechol conjugate for suppression of ROS-induced cells damage and improvement of osteogenesis. Biomaterials 2017, 114, 82-96.

148. Liangliang Dai, Ruisi Cai, Menghuan Li, Zhong Luo, Yonglin Yu, Weizhen Chen, Xinkun Shen, Yuxia Pei, Xiaojing Zhao, Kaiyong Cai*. Dual-Targeted Cascade-Responsive Prodrug Micelle System for Tumor Therapy in Vivo. Chemistry of Materials 2017, 29, 6976-6992.

147. Yuxin Xing, Jixi Zhang*, Feng Chen, Junjie Liu and Kaiyong Cai*. Mesoporous polydopamine nanoparticles with co-delivery function for overcoming multidrug resistance via synergistic chemo-photothermal therapy. Nanoscale 2017, 9, 8781–8790.

146. Jinghua Li*, Fengshou Zhang, Zhigang Hu, Weidong Song, Guangda Li, Gaofeng Liang, Jun Zhou, Ke Li, Yang Cao, Zhong Luo and Kaiyong Cai*. Drug “Pent-Up” in Hollow Magnetic Prussian Blue Nanoparticles for NIR-Induced Chemo-Photothermal Tumor Therapy with Trimodal Imaging. Advanced Healthcare Materials 2017, 6, 1700005.

145. Zhenqiang Wang, Jixi Zhang*, Feng Chen, Kaiyong Cai. Fluorescent miRNA analysis enhanced by mesopore effects of polydopamine nanoquenchers. Analyst 2017, 142(15), 2276-2804.

144. Gaoqiang Xu, Xinkun Shen, Liangliang Dai, Qichun Ran, Pingping Ma, Kaiyong Cai*. Reduced bacteria adhesion on octenidine loaded mesoporous silica nanoparticles coating on titanium substrates. Materials Science and Engineering: C 2017, 70,386-395.

143. Peng Liu*, Yongchun Zhao, Zhang Yuan, Hongyan Ding, Yan Hu, Weihu Yang, Kaiyong Cai*. Construction of Zn-incorporated multilayer films to promote osteoblasts growth and reduce bacterial adhesion. Materials Science and Engineering: C 2017, 75,998-1005.

142. Kui Xu, Weizhen Chen, Caiyun Mu, Yonglin Yu, Kaiyong Cai*. Strontium folic acid derivative functionalized titanium surfaces for enhanced osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo. Journal of Materials Chemistry B 2017, 5, 6811-6826.

141. Jixi Zhang, Kaiyong Cai*. Integration of polymers in the pore space of mesoporous nanocarriers for drug delivery (invited review). Journal of Materials Chemistry B 2017, 5, 8891-8903.

140. Junjie Liu, Didem Sen Karaman, Jixi Zhang*, Jessica M. Rosenholm, Xingming Guo and Kaiyong Cai*. NIR Light-Activated Dual-Modality Cancer Therapy Mediated by Photochemical Internalization of Porous Nanocarriers with Tethered Lipid Bilayer. Journal of Materials Chemistry B 2017, 5, 8289-8298.

139. Peng Liu*, Yansha Hao, Yongchun Zhao, Zhang Yuan, Yao Ding, Kaiyong Cai*. Surface modification of titanium substrates for enhanced osteogenetic and antibacterial properties. Colloids and Surface B-Biointerfaces 2017, 160, 110-116.

138. Ling Huang, Qingfeng Zhang, Liangliang Dai, Xinkun Shen, Weizhen Chen, Kaiyong Cai*. Phenylboronic acid-modified hollow silica nanoparticles for dual-responsive delivery of doxorubicin for targeted tumor therapy. Regenerative Biomaterials 2017,4 (2), 111-124.

137. Jinsong Liu, Zuosu Wu, Hongli He, Kaiyong Cai, Hualin Zhang, Lihua Xu*. Gallium and silicon synergistically promote osseointegration of dental implant in patients with osteoporosis. Medical Hypotheses 2017, 103, 35-38.

136. Tao Ding, Weihu Yang*, Zhong Luo, Ju Liu, Jixi Zhang, Kaiyong Cai*. Preparation of cell pattern on titanium substrates based on upconvertion nanoparticles. Materials Letters 2017, 209, 392-395.

2016年

135. Junjie Liu, Zhong Luo, Jixi Zhang, Tiantian Luo, Jun Zhou, Xiaojing Zhao, Kaiyong Cai*. Hollow mesoporous silica nanoparticles facilitated drug delivery via cascade pH stimuli in tumor microenvironment for tumor therapy. Biomaterials 2016, 83, 51-65.

134. Liangliang Dai, Yonglin Yu, Zhong Luo, Menghuan Li, Weizhen Chen, Xinkun Shen, Feng Chen, Qiang Sun, Qingfeng Zhang, Hao Gu, Kaiyong Cai*. Photosensitizer enhanced disassembly of amphiphilic micelle for ROS-response targeted tumor therapy in vivo. Biomaterials 2016, 104, 1-17.

133. Xinkun Shen, Fei Zhang, Ke Li, Chenhu Qin, Pingping Ma, Liangliang Dai, Kaiyong Cai*. Cecropin B loaded TiO2 nanotubes coated with hyaluronidase sensitive multilayers for reducing bacterial adhesion. Materials & Design2016, 92, 1007-1017.

132. Weihu Yang*, Conghui Deng, Peng Liu, Yan Hu, Zhong Luo, Kaiyong Cai*. Sustained release of aspirin and vitamin C from titanium nanotubes: An experimental and stimulation study. Materials Science and Engineering: C 2016, 64,139-147.

131. Xinkun Shen, Pingping Ma, Yan Hu, Gaoqiang Xu, Kui Xu, Weizhen Chen, Qichun Ran, Liangliang Dai, Yonglin Yu, Caiyun Mu, Kaiyong Cai*. Alendronate-loaded hydroxyapatite-TiO2 nanotubes for improved bone formation in osteoporotic rabbits. Journal of Materials Chemistry B 2016, 4, 1423-1436.

130. Kui Xu, Xinkun Shen, Weizhen Chen, Caiyun Mu, Chao Jiang, Yongchun Zhao, Kaiyong Cai*. Nanosheet-pore topographical titanium substrates: a biophysical regulator of the fate of mesenchymal stem cells. Journal of Materials Chemistry B 2016, 4, 1797-1810.

129. Xianying Zheng, Feng Chen, Jixi Zhang*, Kaiyong Cai*. Silica-assisted incorporation of polydopamine into the framework of porous nanocarriers by a facile one-pot synthesis. Journal of Materials Chemistry B 2016, 4(14), 2435-2443.

128. Liangliang Dai, Qingfeng Zhang, Xinkun Shen, Qiang Sun, Caiyun Mu, Hao Gu, Kaiyong Cai*. A pH-responsive nanocontainer based on hydrazone-bearing hollow silica nanoparticles for targeting tumor therapy. Journal of Materials Chemistry B 2016, 4, 4594 - 4604.

127. Kui Xu, Weizhen Chen, Yan Hu, Xinkun Shen, Gaoqiang Xu, Qichun Ran, Yonglin Yu, Caiyun Mu, Kaiyong Cai*. Influence of strontium ions incorporated nanosheet-pore topographical titanium substrates on osteogenic differentiation of mesenchymal stem cells in vitro and osseointegration in vivo. Journal of Materials Chemistry B 2016, 4, 4549 - 4564.

126. Liangliang Dai, Junjie Liu, Zhong Luo, Menghuan Li, Kaiyong Cai*. Tumor therapy: targeted drug delivery system. Journal of Materials Chemistry B 2016, 4, 6758 - 6772.

125. Xinkun Shen, Yarong Zhang, Yan Hu*, Zhong Luo, Pingping Ma, Liqi Li, Caiyun Mu, Ling Huang, Yuxia Pei and Kaiyong Cai*. Regulation of local bone remodeling mediated by hybrid multilayer coating embedded with hyaluronan-alendronate/BMP-2 nanoparticles on Ti6Al7Nb implants. Journal of Materials Chemistry B 2016, 4, 7101 - 7111.

124. Feng Chen, Yuxin Xing, Zhenqiang Wang, Xianying Zheng, Jixi Zhang*, Kaiyong Cai. Nanoscale polydopamine (PDA) meets Π−Π interactions: An interface-directed coassembly approach for mesoporous nanoparticles. Langmuir 2016, 32 (46), 12119–12128.

123. Ling Huang, Zhong Luo, Yan Hu*, Xinkun Shen, Menghuan Li, Liqi Li, Yuan Zhang, Weihu Yang, Peng Liu, Kaiyong Cai*. Enhancement of local bone remodeling in osteoporotic rabbits by biomimic multilayered structures on Ti6Al4V implants. Journal of Biomedical Materials Research Part A 2016, 104 (6), 1437-1451.

122. Xiaoping Yao, Xianying Zheng, Jixi Zhang*, Kaiyong Cai*. Oxidation-induced surface deposition of tannic acid: towards molecular gates on porous nanocarriers for acid-responsive drug delivery. RSC Advances 2016, 6, 76473-76481.

121. Zhang Yuan, Yongchun Zhao, Weihu Yang, Yan Hu, Kaiyong Cai, Peng Liu, Hongyan Ding. Fabrication of antibacterial surface via UV-inducing dopamine polymerization combined with co-deposition Ag nanoparticles. Materials Letters 2016, 18, 85-89.

2015年

120. Liangliang Dai, Qingfeng Zhang, Jinghua Li, Xinkun Shen, Caiyun Mu, and Kaiyong Cai*. Dendrimer-Like Mesoporous Silica Nanoparticles as pH-responsive Nanocontainers for Targeted Drug Delivery and Bioimaging. ACS Applied Materials & Interfaces 2015, 7 (13), 7357-7372.

119. Jinghua Li, Yan Hu, Yanhua Hou, Xinkun Shen, Gaoqiang Xu, Liangliang Dai, Jun Zhou, Yun Liu and Kaiyong Cai*. Phase-change material filled hollow magnetic nanoparticles for cancer therapy and dual modal bioimaging. Nanoscale 2015, 7, 9004-9012.

118. Junjie Liu, Beilu Zhang, Zhong Luo, Xingwei Ding, Jinghua Li, Liangliang Dai, Jun Zhou, Xiaojing Zhao, Jingya Ye and Kaiyong Cai*. Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo. Nanoscale 2015, 7, 3614-3626.

117. Sha He, Yi Zhang, Pei Wang, Xingzhi Xu, Kui Zhu, Wenying Pan, Wenwen Liu, Kaiyong Cai*, Jiashu Sun*, Wei Zhang and Xingyu Jiang*. Multiplexed microfluidic blotting of proteins and nucleic acids by parallel, serpentine microchannels. Lab on a Chip 2015, 15, 105-112.

116. Peng Liu*, Yongchun Zhao, Ying Yan, Yan Hu, Weihu Yang, Kaiyong Cai*. Construction of extracellular microenvironment to improve surface endothelialization of NiTi alloy substrate. Materials Science and Engineering C 2015, 55 (1), 1-7.

115. Linhao Li, Yuna Qian, Chongwen Lin, Haibin Li, Chao Jiang, Yonggang Lv, Wanqian Liu, Kaiyong Cai, Oliver Germershaus and Li Yang. The effect of silk gland sericin protein incorporation into electrospun polycaprolactone nanofibers on in vitro and in vivo characteristics. Journal of Materials Chemistry B 2015, 3, 859-870.

114. Liangliang Dai, Qingfeng Zhang, Hao Gu, Kaiyong Cai*. Facile synthesis Yolk-shell silica nanoparticles for targeting tumor therapy. Journal of Materials Chemistry B 2015, 3, 8303 -8313.

113. Xinkun Shen, Pingping Ma, Yan Hu, Gaoqiang Xu, Jun Zhou, Kaiyong Cai*. Mesenchymal stem cell growth behavior on micro/nano hierarchical surfaces of titanium substrates. Colloids and Surface B-Biointerfaces 2015, 127, 221-232.

112. Xianying Zheng, Jixi Zhang, Jie Wang, Xueqiang Qi, Jessica M. Rosenholm, Kaiyong Cai. Polydopamine coatings in confined nanopore space: toward improved retention and release of hydrophilic cargo. The Journal of Physical Chemistry C 2015, 119, 24512-24521.

111. Yuna Qian, Linhao Li, Chao Jiang, Wei Xu, Yonggang Lv, Li Zhong, Kaiyong Cai, Li Yang. The effect of hyaluronan on the motility of skin dermal fibroblasts in nanofibrous scaffolds. International Journal of Biological Macromolecules 2015, 79, 133-143.

110. Jun Zhou, Jinghua Li, Xingwei Ding, Junjie Liu, Zhong Luo, Yun Liu, Qichun Ran, Kaiyong Cai*. Multifunctional Fe2O3@PPy-PEG nanocomposite for MRI-guided combination cancer therapy. Nanotechnology 2015 (26) 425101.

109. Yun Liu, Xingwei Ding, Jinghua Li, Zhong Luo, Yan Hu, Junjie Liu, Liangliang Dai, Jun Zhou, Changjun Hou, Kaiyong Cai*. Enzyme responsive drug delivery system based on mesoporous silica nanoparticles for tumor therapy in vivo. Nanotechnology 2015, 26, 145102.

108. Min Lai, Christopher D. Hermann, Rene Olivares-Navarrete, Alice Cheng, Rolando A. Gittens, Marcus Walker, Ye Cai, Kaiyong Cai, Kenneth H. Sandhage, Zvi Schwartz, and Barbara D. Boyan. Role of α2β1Integrins in Mediating Cell Shape on Microtextured Titanium Surfaces. Journal of Biomedical Materials Research Part A 2015, 103(2): 564-573.

107. Gaoqiang Xu, Xinkun Shen, Yan Hu, Pingping Ma, Kaiyong Cai*. Fabrication of tantalum oxide layers onto titanium substrates for improved corrosion resistance and cytocompatibility. Surface & Coatings Technology 2015, 272: 58-65.

106. Yarong Zhang, Yan Hu*, Zhong Luo, Xinkun Shen, Caiyun Mu and Kaiyong Cai*. Simultaneous Delivery of BMP-2 Factor and Anti-osteoporotic Drugs Using Hyaluronan-assembled Nanocomposite for Synergistic Regulation on the Behaviors of Osteoblasts and Osteoclasts in Vitro. Journal of Biomaterials Science: Polymer Edition 2015, 26(5):290-310.

105. Yan Hu, Kaiyong Cai*. “Polyelectrolyte Multilayer Film for the Regulation of Stem Cells in Orthopedic Fields”, “Layer-by-Layer Films for Biomedical Applications (Edited by Picart, Caruso, Voegel)”, Wiley-VCH, 2015, 30 JAN, 507-521.

104. Yuran Huang, Tuo Wei, Jing Yu, Yanglong Hou, Kaiyong Cai*, Xinjie Liang*. Multifunctional metal rattle-type nanocarriers for MRI-guided photothermal cancer therapy. Colloidal Nanoparticles for Biomedical Applications X. 2015, Vol: 9338, 933803.

2014年

103. Zhong Luo, Yan Hu*, Kaiyong Cai, Xingwei Ding, Quan Zhang, Menghuan Li, Xing Ma, Beilu Zhang, Yongfei Zeng, Peizhou Li, Jinghua Li, Junjie Liu, Yanli Zhao. Intracellular redox-activated anticancer drug delivery by functionalized hollow mesoporous silica nanoreservoirs with tumor specificity. Biomaterials 2014, 35: 7951-7962.

102. Xingwei Ding, Yun Liu, Jinghua Li, Zhong Luo, Yanhua Hou, Yan Hu, Beilu Zhang, Junjie Liu, Jun Zhou and Kaiyong Cai*. Hydrazone-Bearing PMMA-Functionalized Magnetic Nanocubes as pH-Responsive Drug Carriers for Remotely Targeted Cancer Therapy in Vitro and in Vivo. ACS Applied Materials & Interfaces 2014, 6: 7395-7407.

101. Xinkun Shen, Yan Hu, Gaoqiang Xu, Weizhen Chen, Kui Xu, Qichun Ran, Pingping Ma, Yarong Zhang, Jinghua Li, Kaiyong Cai*. Regulation of the Biological Functions of Osteoblasts and Bone Formation by Zn-Incorporated Coating on Microrough Titanium. ACS Applied Materials & Interfaces 2014, 6 (18), 16426–16440.

100. Beilu Zhang, Zhong Luo, Junjie Liu, Xingwei Ding, Jinghua Li and Kaiyong Cai*. Cytochrome c end-capped mesoporous silica nanoparticles as redox-responsive drug delivery vehicles for liver tumor-targeted triplex therapy in vitro and in vivo. Journal of Controlled Release 2014, 192: 192-201.

99. Weihu Yang, Xingfeng Xi, Yang Si, Song Huang, Jiangfeng Wang, Kaiyong Cai*. Surface engineering of titanium alloy substrates with multilayered biomimetic hierarchical films to regulate the growth behaviors of osteoblasts. Acta Biomaterialia 2014, 10 (10), 4525-4536.

98. Weihu Yang, Xingfeng Xi, Qichun Ran, Peng Liu, Yan Hu, Kaiyong Cai*. Influence of the titania nanotubes dimensions on adsorption of collagen: An experimental and computational study. Materials Science and Engineering: C 2014, 34, 410-416.

97. Jingfeng Wang, Yang Li, Song Huang, Yiyun Wei, Xingfeng Xi, Kaiyong Cai, Fusheng Pan. Effects of Y on the Microstructure, Mechanical and Bio-corrosion Properties of Mg-Zn-Ca Bulk Metallic Glass. Journal of Materials Science & Technology 2014, 30 (12): 1255-1261.

96. Lu Zhao, Yan Hu, Dawei Xu, Kaiyong Cai*. Surface functionalization of titanium substrates with chitosan-lauric acid conjugate to enhance osteoblasts functions and inhibits bacteria adhesion. Colloids and Surface B-Biointerfaces 2014, 119: 115-125.

95. Pian Wu, Ya Fu*, Kaiyong Cai*. Regulation of the migration of endothelial cells by a density gradient of vascular endothelial growth factor. Colloids and Surface B-Biointerfaces 2014, 123, 181-190.

94. Yuran Huang, Tuo Wei, Jing Yu, Yanglong Hou, Kaiyong Cai* and Xing-Jie Liang*. Multifunctional metal rattle-type nanocarriers for MRI guided photothermal cancer therapy. Molecular Pharmaceutics 2014, 11, 3386-3394.

93. Yanhua Hou, Min Lai, Xiuyong Chen, Jinghua Li, Yan Hu, Zhong Luo, Xingwei Ding, Dawei Xu, Yun Liu and Kaiyong Cai*. Effects of mesoporous SiO2, Fe3O4 and TiO2 on the biological functions of endothelial cells in vitro. Journal of Biomedical Materials Research Part A 2014, 102(6): 1726–1736.

92. Weihu Yang, Xingfeng Xi, Xiuyong Chen, Peng Liu, Yan Hu, Kaiyong Cai*. Titania nanotubes dimensions-dependent protein adsorption and its effect on the growth of osteoblasts. Journal of Biomedical Materials Research Part A 2014, 102: 3598–3608.

91. Zhong Luo, Yan Hu, Renlong Xin, Beilu Zhang, Jinghua Li, Xingwei Ding, Yanhua Hou, Li Yang, Kaiyong Cai*. Surface functionalized mesoporous silica nanoparticles with natural proteins for reduced immunotoxicity. Journal of Biomedical Materials Research Part A 2014, 102, 3781-3794.

90. Liangliang Dai, Jinghua Li, Beilu Zhang, Junjie Liu, Zhong Luo, Kaiyong Cai*. Redox-Responsive Nanocarrier Based on Heparin End-Capped Mesoporous Silica Nanoparticles for Targeted Tumor Therapy in Vitro and in Vivo. Langmuir 2014, 30: 7867-7877.

89. Jinghua Li, Yanhua Hou, Xiuyong Chen, Xingwei Ding, Yun Liu, Xinkun Shen and Kaiyong Cai*. Recyclable heparin and chitosan conjugated magnetic nanocomposites for selective removal of low-density lipoprotein from plasma. Journal of Materials Science: Materials in Medicine 2014, 25 (4): 1055-1064.

88. Wen Li, Dawei Xu, Yan Hu*, Kaiyong Cai, Yingcheng Lin. Surface modification of titanium substrates with silver nanoparticles embedded sulfhydrylated chitosan/ gelatin polyelectrolyte multilayer films for antibacterial application. Journal of Materials Science: Materials in Medicine 2014, 25: 1435-1448.

87. Sheng Yang, Ming Wang, He Zhang, Kaiyong Cai, Xin-kun Shen, Feng Deng, Yi Zhang and Lu Wang. Influence of dexamethasone-loaded TNTs on the proliferation and osteogenic differentiation of rat mesenchymal stem cells. RSC Advancesances 2014, 4, 65163- 65172.

86. Ying Yan, Weihu Yang, Yan Hu, Kaiyong Cai, Peng Liu. Surface modification of NiTi alloy via a TiN coating functionalized with biomimic multilayer films. Materials Letters 2014, 120: 155-158.

85. Congjun Liu, Yongchun Zhao, Yashao Chen, Peng Liu, Kaiyong Cai. Surface modification of magnesium alloy via cathodic plasma electrolysis and its influence on corrosion resistance and cytocompatibility. Materials Letters 2014, 132: 15-18.

84. Min Lai, Kaiyong Cai*, Xiaofang Yang, Qing Liu, Jinghua Li, Yanhua Hou, Xiuyong Chen. The surface nanostructures of titanium alloy regulate the proliferation of endothelial cells. AIMS Materials Science 2014; 1(1): 45-48.

83. Jinsong Liu, Hualin Zhang, Yiwen Dong, Yifan Jin, Xiaohui Hu, Kaiyong Cai*, Jianfeng Ma*, Gang Wu. Bi-directionally selective bone targeting delivery for anabolic and antiresorptive drugs: A novel combined therapy for osteoporosis? Medical Hypotheses 2014; 83(6):694-696.

2013年

82. Zhong Luo, Xingwei Ding, Yan Hu, Shaoquan Wu, Yang Xiang, Yongfei Zeng, Hong Yan, Hua-cheng Zhang, Liangliang Zhu, Junjie Liu, Jinghua Li, Kaiyong Cai*, Yanli Zhao*. Engineering a Hollow Nanocontainer Platform with Multifunctional Molecular Machines for Tumor-Targeted Therapy in Vitro and in Vivo. ACS Nano 2013; 7(11): 10271-10284.

81. Yuran Huang, Kaiyong Cai*, Xinjie Liang*. Multifunctional magnetic polymeric nanoparticles: A theranostic platform for multimodal cancer imaging and therapeutics. Journal of Controlled Release 2013, 172(1): E93-E93.

80. Jingfeng Wang, Song Huang, Yang Li, Yiyun Wei, Xingfeng Xi, Kaiyong Cai. Microstructure, mechanical and bio-corrosion properties of Mn-doped Mg–Zn–Ca bulk metallic glass composites. Materials Science and Engineering: C 2013, 33(7):3832-3838.

79. Weihu Yang, Xingfeng Xi, Jiajia Fang, Peng Liu, Kaiyong Cai*. Influences of magnetized hydroxyapatite on the growth behaviors of osteoblasts and the mechanism from molecular dynamics simulation. Materials Science and Engineering: C 2013,33:3753-3759.

78. Yanhua Hou, Kaiyong Cai*, Jinghua Li, Xiuyong Chen, Min Lai, Yan Hu, Zhong Luo, Xingwei Ding,Dawei Xu. Effects of titanium nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells. International Journal of Nanomedicine 2013, 8, 3619- 3630.

77. Xiuyong Chen, Kaiyong Cai*, Jiajia Fang, Min Lai, Yanhua Hou, Jinghua Li, Zhong Luo, Yan Hu, Liling Tang. Fabrication of selenium-deposited and chitosan-coated titania nanotubes with anticancer and antibacterial properties. Colloids and Surface B-Biointerfaces 2013; 103: 149-157.

76. Dawei Xu, Weihu Yang*, Yan Hu, Zhong Luo, Jinghua Li, Yanhua Hou, Yun Liu, Kaiyong Cai*. Surface functionalization of titanium substrates with Cecropin B to improve their cytocompatibility and reduce inflammation responses. Colloids and Surface B-Biointerfaces 2013; 110:225-235.

75. Min Lai, Kaiyong Cai*, Yan Hu, Yuan Zhang, Liqi Li, Zhong Luo, Yanhua Hou, Jinghua Li, Xingwei Ding, Xiuyong Chen. Construction of microenvironment onto titanium substrates to regulate the osteoblastic differentiation of bone marrow stromal cells in vitro and osteogenesis in vivo. Journal of Biomedical Materials Research Part A 2013, 101A: 653–666.

74. Daichao Xie, Kaiyong Cai*,Yan Hu, Zhong Luo. Surface engineering of titanium substrates with chitosan-atorvastatin conjugate for reduced inflammation responses and improved cytocompatibility. Journal of Biomedical Materials Research Part A 2013, 101A: 2005-2014.

73. Ying Yan, Kaiyong Cai, Weihu Yang, Peng Liu. Surface modification of NiTi alloy via cathodic plasma electrolytic deposition and its effect on Ni Ion release and osteoblast behaviors. Plasma Science & Technology 2013, 15(7): 648-653.

72. Xiuyong Chen, Kaiyong Cai*, Jiajia Fang, Min Lai, Jinghua Li, Yanhua Hou, Zhong Luo, Yan Hu, Liling Tang. Dual action antibacterial TiO2 nanotubes incorporated with silver nanoparticles and coated with a quaternary ammonium salt (QAS). Surface & Coatings Technology 2013, 216; 158-165.

71. Yang WH, Xi XF, Li JF, Cai KY. Comparison of crystal structure between carbonated hydroxyapatite and natural bone apatite with theoretical calculation. Asian Journal of Chemistry 2013, 25(7): 3673-3678.

2012年

70. Zhong Luo, Kaiyong Cai*, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, Weihu Yang, Peng Liu. Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles. Advanced Materials 2012, 24, 431-435.

69. Linhao Li, Yuna Qian, Chao Jing, Yonggang Lv, Wanqian Liu, Li Zhong, Kaiyong Cai, Song Li, Li Yang. The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds. Biomaterials 2012;33(12):3428-3445.

68. Yan Hu, Kaiyong Cai*, Zhong Luo, Yuan Zhang, Liqi Li, Min Lai, Yanhua Hou, Yuran Huang, Jinghua Li, Xingwei Ding, Bin Zhang, K L Paul Sung. Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces. Biomaterials 2012; 33(13):3515-3528.

67. Zhong Luo, Kaiyong Cai*, Yan Hu, Beilu Zhang, Dawei Xu. Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH-sensitivity. Advanced Healthcare Materials 2012; 1:321-325.

66. Yan Hu, Kaiyong Cai*, Zhong Luo, Dawei Xu, Daichao Xie, Yuran Huang, Weihu Yang, Peng Liu. TiO2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells. Acta Biomaterialia 2012; 8:439-448.

65. Xingwei Ding, Kaiyong Cai*, Zhong Luo, Jinghua Li, Yan Hu and Xinkun Shen. Biocompatible magnetic liposomes for temperature triggered drug delivery. Nanoscale 2012, 4:6289-6292.

64. Yuran Huang, Sha He, Weipeng Cao, Kaiyong Cai*, Xingjie Liang*. Biomedical nanomaterials for imaging-guided cancer therapy. Nanoscale 2012, 4, 6135-6149.

63. Weixing Shen, Kaiyong Cai, Zaixiang Yang, Ying Yan, Weihu Yang, Peng Liu. Improved endothelialization of NiTi alloy by VEGF functionalized nanocoating. Colloids and Surface B-Biointerfaces 2012; 94: 347-353.

62. Min Lai, Kaiyong Cai*, Yan Hu, Xiaofang Yang, Qing Liu. Regulation of the behaviors of mesenchymal stem cells by surface nanostructured titanium. Colloids and Surface B-Biointerfaces 2012; 97C: 211-220.

61. Xiuyong Chen, Kaiyong Cai*, Min Lai, Li Zhao, Liling Tang. Mesenchymal stem cells differentiation on hierarchically micro/nano-structured titanium substrates. Advanced Biomaterials 2012, 14(5):B216-223.

60. Peng Liu, Xin Pan, Weihu Yang, Kaiyong Cai, Yashao Chen. Al2O3-ZrO2 ceramic coatings fabricated on WE43 magnesium alloy by cathodic plasma electrolytic deposition. Materials Letters 2012; 70 (1): 16-18.

59. Peng Liu, Xin Pan, Weihu Yang, Kaiyong Cai, Yashao Chen. Improved anticorrosion of magnesium alloy via layer-by-layer self-assembly technique combined with micro-arc oxidation. Materials Letters 2012; 75: 118-121.

2011年

58. Zhong Luo, Kaiyong Cai*, Yan Hu, Li Zhao, Peng Liu, Lin Duan, Weihu Yang. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. Angewandte Chemie International Edition. 2011;50(3) :640-643.

57. Kaiyong Cai*, Yanhua Hou, Yan Hu, Li Zhao, Zhong Luo, Yisong Shi, Min Lai, Weihu Yang, Peng Liu. Correlation of the cytotoxicity of TiO2 nanoparticles with different particle sizes on a sub-200-nm scale. Small 2011; 7(21):3026-3031.

56. Kaiyong Cai*, Jinghua Li, Zhong Luo, Yan Hu, Yanhua Hou, Xingwei Ding. beta-Cyclodextrin conjugated magnetic nanoparticles for diazepam removal from blood. Chemical Communications 2011, 47 (27), 7719 – 7721.

55. Min Lai, Kaiyong Cai*, Li Zhao, Xiuyong Chen, Yanhua Hou, Zaixiang Yang. Surface functionalization of TiO2 nanotubes with bone morphogenetic protein 2 and its synergistic effect on the differentiation of mesenchymal stem cells. Biomacromolecules 2011, 12 (4): 1097-1105.

54. Kaiyong Cai*, Xiaojing Sui, Yan Hu, Li Zhao, Min Lai, Zhong Luo, Peng Liu, Weihu Yang. Fabrication of anticorrosive multilayer onto magnesium alloy substrates via spin-assisted layer-by-layer technique. Materials Science and Engineering: C 2011; 31:1800-1808.

53. Linhao Li, Haibin Li, Yuna Qian, Xian Li, Gurinder K. Singh, Li Zhong, Wanqian Liu, Yonggang Lv, Kaiyong Cai and Li Yang, Electrospun poly (epsilon-caprolactone)/silk fibroin core-sheath nanofibers and their potential applications in tissue engineering and drug release. Intern J Biological Macromolecules 2011;49(2):223-232.

52. Jimin Xu, Cheng Chen, Xuemei Jiang, Rong Xu, Dhananjay Tambe, Xiaojuan Zhang, Lina Liu, Bo Lan, Kaiyong Cai, Linhong Deng. Effects of micropatterned curvature on the motility and mechanical properties of airway smooth muscle cells. Biochemical and Biophysical Research Communications 2011; 415(4):591-596.

51. Sha He, Dingbin Liu, Zhuo Wang, Kaiyong Cai*, Xingyu Jiang*. Utilization of unmodified gold nanoparticles in colorimetric detection. Science China G: physics, mechanics & Astronomy 2011;54(10):1757-1765.

50. Yequan Wang, Zhenyu Tang, Ruyue Xue, Gurinder K. Singh, Yonggang Lv, Kunning Shi, Kaiyong Cai, Linhong Deng, Li Yang. TGF-beta 1 promoted MMP-2 mediated wound healing of anterior cruciate ligament fibroblasts through NF-kappa B. Connective Tissue Research 2011, 52 (3), 218-225(8).

49. Weihu Yang, Jiajia Fang, Peng Liu, Junfeng Li, Kaiyong Cai. Theoretical study of the permeation of water through TiO2 nanotubes using molecular dynamics simulation. Molecular Physics 2011,109(6), 969 – 974.

48. Zhong Luo, Kaiyong Cai*, Beilu Zhang, Lin Duan, Aiping Liu, Duan Gong. Application of mesoporous silica nanoreservoir in smart drug controlled release systems. Progress in Chemistry 2011;23(11):151-163.

2010年

47. Yan Hu, Kaiyong Cai*, Zhong Luo, Klaus D. Jandt. Layer-By-Layer Assembly of beta-estradiol loaded mesoporous silica nanoparticles on titanium substrates and its implication for bone homeostasis. Advanced Materials 2010; 22(37):4146-4150.

46. Kaiyong Cai*, Min Lai, Ran Hu, Renlong Xin, Qing Liu, K. L. Paul Sung. Surface engineering of titanium with potassium hydroxide and its effects on the growth behavior of mesenchymal stem cells. Acta Biomaterialia 2010; (6)2314-2321.

45. Kaiyong Cai*, Tingting Kong, Lu Wang, Peng Liu, Weihu Yang, Chong Chen. Regulation of endothelial cells migration on poly(D, L-lactic acid) films immobilized with collagen gradients. Colloids and Surface B-Biointerfaces 2010;79:291-297.

44. Kaiyong Cai*, Feng Jiang, Zhong Luo, Xiuyong Chen. Temperature-responsive controlled drug delivery system based on titanium nanotubes. Advanced Biomaterials 2010; 12(9): B 565-B 570.

43. Kaiyong Cai*, Klaus D Jandt. Foundation for Chinese-german cooperation in advanced biomedical nanostructures laid. Advanced Biomaterials 2010; 12(9): B 396-B397.

42. Yan Hu, Kaiyong Cai*, Zhong Luo, Ran Hu. Construction of polyethyleneimine -beta-cyclodextrin/pDNA multilayer structure for improved in situ gene transfection. Advanced Engineering Materials 2010:12(1-2):B18-B25.

41. 睢晓静,蔡开勇;镁合金表面铈多层膜的抗腐蚀性及细胞相容性研究。材料导报,2010, 24(8): 53-56.

2009年

40. Kaiyong Cai*, Zhong Luo, Yan Hu, Xiuyong Chen, Li Yang, Linhong Deng. Magnetically triggered reversible controlled drug delivery from microfabricated polymeric multireservoir devices. Advanced Materials 2009; 21(40): 4045-4049.

39. Yan Hu, Kaiyong Cai*, Rui Zhang, Zhong Luo, Li Yang, Klaus D. Jandt, Linhong Deng. Surface mediated in situ differentiation of mesenchymal stem cells on gene-functionalized titanium films fabricated by layer-by-layer technique. Biomaterials 2009; 30(21):3626-3635.

38. Kaiyong Cai*, Haide Dong, Chong Chen, Li Yang, Linhong Deng, Klaus D. Jandt. Inkjet printing of laminin gradient to investigate endothelial cellular alignment. Colloids and Surface B-Biointerfaces 2009; 72(2): 230-235.

37. Yan Hu, Kaiyong Cai*, Zhong Luo, Chong Chen, Haide Dong, Jianyuan Hao, Li Yang, Linhong Deng. Fabrication of galactosylated polyethylenimine and plasmid DNA multilayers on poly (D,L-lactic acid) films for in situ targeted gene transfection. Advanced Engineering Materials 2009; 11 (5): B30-B34.

36. 陈冲,蔡开勇*Siegmund Schroeter;同一基底材料表面不同蛋白浓度域与人脐静脉内皮细胞相互作用的初步研究。中国修复重建外科杂志 2009年23卷5期617-622.

2008年

35. Kaiyong Cai*, Yan Hu, Zhong Luo, Ting Kong, Min Lai, Xiaojing Sui, Yuanliang Wang, Li Yang and Linhong Deng. Cell-specific gene transfection from a gene-functionalized poly(D,L-lactic acid) substrate fabricated by the layer-by-layer assembly technique. Angewandte Chemie International Edition 2008; 47(39): 7479-7481.

34. Kaiyong Cai*, Yan Hu, Yuanliang Wang, Li Yang. Build up of multilayered thin films with chitosan/DNA pairs on poly(D,L-lactic acid) films: Physical chemistry and sustained release behavior. Journal of Biomedical Materials Research Part A 2008; 84A (2): 516-522.

33. Kaiyong Cai*, Yan Hu, Klaus D. Jandt. Surface modification of titanium thin film with chitosan via electrostatic self-assembly technique and its influence on osteoblast growth behavior. Journal of Materials Science - Materials in Medicine 2008; 19(2): 499-506.

32. Jianyuan Hao, Thomas Keller, Kaiyong Cai, Elisabeth Klemm, Jörg Bossert, Klaus D Jandt. The effect of D,L-lactidyl/epsilon-caproyl weight ratio and chemical microstructure on surface properties of biodegradable poly (D,L-lactide)-co-poly (epsilon-caprolactone) random copolymers. Advanced Engineering Materials 2008; 10(8):B23-B32.

31. Kaiyong Cai*, Cong Chen, Sigemund Schroeter, Linhong Deng, Li Yang. Modulation motility of endothelial cells via culture microenvironment with various curvatures. Biorheology 2008, 45(1,2): 124-125.

30. Linhong Deng, Jinming Xu, Yashu Wang, Kaiyong Cai, Qiang Chen, Cong Chen, Yayue. Chen, Aijin Song. Rheological properties of airway smooth muscle cells vary according to the curvature of micro-patterns in which the cell is cultured: Is tissue curvature a geometric cue for regulation of cellular mechanics along the bronchial track? Biorheology 2008, 45(1, 2): 171.

29. Kaiyong Cai*. Composite hydrogel: novel hydrogel for tissue engineering. Bioforum Europe 2008,12:27-29.

28. 胡燕, 蔡开勇*;层层自组装技术在基因活化生物材料表面工程的应用。生物医学工程学杂志  2008, 25(3):738-741.

27. 陈欣,胡燕,蔡开勇*,王远亮;基因活化聚乳酸表面工程的初步研究。重庆大学学报(自然科学版). 2008年01期,93-97.

2007年

26. Kaiyong Cai*, Kangde Yao, Zhiming Yang, Yanlong Qu, Xiuqiong Li. Surface modification of three-dimensional poly(D,L-lactic acid) scaffolds with baicalin: A histological study. Acta Biomaterialia 2007; 3(4): 597-605.

25. Kaiyong Cai*, Yan Hu, Klaus D. Jandt. Surface engineering of titanium thin films with silk fibroin via layer-by-layer technique and its effects on osteoblast growth behavior. Journal of Biomedical Materials Research Part A 2007; 82A(4) : 927-935.

24. Kaiyong Cai*, Kangde Yao, Zhiming Yang, Yanlong Qu, Xiuqiong Li. Histological study of surface modified three dimensional poly(D,L-lactic acid) scaffolds with chitosan in vivo. Journal of Materials Science-Materials in Medicine 2007,18: 2017-2024.

23. Klaus D. Jandt, Kaiyong Cai. Guest editorial. Advanced Engineering Materials 2007; 9(12): 1023-1024.

22. Kaiyong Cai*, Jun Zhang, Yan Hu, Lei Xu. Physical and biological properties of a novel hydrogel composite based on oxidized alginate, gelatin and tricalcium phosphate for bone tissue engineering. Advanced Engineering Materials 2007; 9(12): 1082-1088.

21. Kaiyong Cai*. Surface modification of titanium films with sodium ion implantation: surface properties and protein adsorption. Acta Metallurgica Sinica (English Letters) 2007; 20(2): 148-156.

20. 蔡开勇;纳米生物材料及其界面特性对成骨细胞生长影响的研究进展。材料导报,2007; 21(2): 109-112.

2006年

19. Kaiyong Cai, Klaus D Jandt. Does the nanometre scale topography of titanium influence protein adsorption and cell proliferation? Colloids and Surface B-Biointerfaces 2006; 49(2): 136-144.

18. Kaiyong Cai, Marion Frant, Jörg Bossert, Gerhard Hildebrand, Klaus Liefeith, Klaus D. Jandt. Surface functionalized titanium thin films: Zeta-potential, protein adsorption and cell proliferation. Colloids and Surface B-Biointerfaces 2006; 50(1): 1-8.

17. Kaiyong Cai*, Yuanliang Wang. Polysaccharide surface engineering of poly(D, L-lactic acid) via electrostatic self-assembly technique and its effects on osteoblast growth behaviours. Journal of Materials Science-Materials in Medicine 2006; 17(10): 929-935.

2005年及以前

16. Kaiyong Cai, Annett Rechtenbach, Jianyuan Hao, Jörg Bossert, Klaus D. Jandt. Polysaccharide-protein surface modification of titanium via a layer-by-layer technique: Characterization and cell behaviour aspects. Biomaterials 2005; 26 (30): 5960-5971.

15. Kaiyong Cai, Kangde Yao, Songbai Lin, Zhiming Yang et al. Poly(D,L-lactic acid) surfaces modified by silk fibroin: effects on the culture of osteoblast in vitro. Biomaterials 2002; 23(4): 1153-1160.

14. Kaiyong Cai, Kangde Yao, Yuanlu Cui, Zhiming Yang et al. Influence of different surface modification treatments on poly(D,L-lactic acid) with silk fibroin and their effects on the culture of osteoblast in vitro. Biomaterials 2002; 23(7): 1603-1611.

13. Kaiyong Cai, Michael Müller, Jörg Bossert, Annett Rechtenbach, Klaus D. Jandt. Surface structure and composition of flat titanium thin films as a function of film thickness and evaporation rate. Applied Surface Science 2005; 250/1-4: 252-267.

12. Kaiyong Cai, Kangde Yao, Yuanlu Cui, Songbai Lin, Zhiming Yang et al. Surface modification of poly (D,L-lactic acid) with chitosan and its effects on the culture of osteoblasts in vitro. Journal of Biomedical Materials Research Part A 2002; 60(3): 398-404.

11. Kaiyong Cai, Kangde Yao, Songbai Lin, Zhiming Yang et al. Modulation of osteoblast function using poly(D,L-lactic acid) surfaces modified with alkylation derivative of chitosan. Journal of Biomaterials Science: Polymer Edition 2002; 13(1): 53-66.

10. Kaiyong Cai, Kangde Yao, Xin Hou, YQ Wang, YJ Hou, ZM Yang, XQ Li, HQ Xie. Improvement of the functions of osteoblasts seeded on modified poly(D,L-lactic acid) with poly(aspartic acid). Journal of Biomedical Materials Research Part A 2002; 62(2): 283-291.

9. Kaiyong Cai, Kangde Yao, Songbai Lin, Zhiming Yang et al. Rat osteoblast functions on the o-carboxymethyl chitosan-modified poly(D,L-lactic acid) surface. Journal of Biomaterials Science: Polymer Edition 2001; 12(12): 1303-15.

8. Kaiyong Cai, Songbai Lin, Kangde Yao. Advances in research on surface engineering of biomaterials for tissue engineering. Progress in Chemistry 2000;13(1): 56-64.

7. Yuji Yin, Kaiyong Cai, Xiangshi Li, Kangde Yao, Zhiming Yang, Xiuqiong Li, Huiqi Xie. Modulation of poly(D,L-lactic acid) with amniotic fluid for improvement of the cell affinity. Materials Science and Engineering: C 2005; 25:503-508

6. Songbai Lin, Jihuai Wu, Kangde Yao, Kaiyong Cai, Chunmei Xiao; Chanjie Jiang. Study of microstructure and properties of HEC-g-AA/SiO2 organic-inorganic hybrid materials. Composite Interface 2004, 11 (3): 271-276.

5. Yuan Lu Cui, Xin Hou, Ai Di Qi, Xiang Hui Wang, Kaiyong Cai, Yu Ji Yin, Kang De Yao. Biomimetic surface modification of poly (L-lactic acid) with gelatin and its effects on articular chondrocytes in vitro. Journal of Biomedical Materials Research Part A 2003, 66A: 770-778.

4. Wenguan Liu, Xinwei Li, Kaiyong Cai, Kangde Yao. Effects of baicalin-modified poly(D,L-lactic acid) surface on the behavior of osteoblasts. Journal of Materials Science - Materials in Medicine 2003, 14(11): 961-965.

3. 蔡开勇, 姚康德;组织工程生物材料的表面修饰。康复理论2002,8 (5): 263-267.

2. 尹玉姬,姚康德,刘文广,毛津淑,崔元璐,蔡开勇,赵峰;组织工程相关壳聚糖-明胶基生物材料。应用化学,2004, 21 (3): 217-222.

1. 姚康德,沈峰,蔡开勇,宋雪峰等;组织工程相关生物材料的仿生表面修饰。中华整形外科杂志,2000, 16(6): 331-332.



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